"HLA-C Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
| Descriptor ID |
D015236
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| MeSH Number(s) |
D12.776.395.550.489.600 D12.776.543.550.439.600 D23.050.301.500.100.600 D23.050.301.500.450.390 D23.050.705.552.100.600 D23.050.705.552.450.390
|
| Concept/Terms |
HLA-C Antigens- HLA-C Antigens
- HLA C Antigens
- HLA-C
- Antigens, HLA-C
- Antigens, HLA C
|
Below are MeSH descriptors whose meaning is more general than "HLA-C Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-C Antigens".
This graph shows the total number of publications written about "HLA-C Antigens" by people in this website by year, and whether "HLA-C Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 13 | 2 | 15 |
| 2018 | 9 | 0 | 9 |
| 2019 | 4 | 0 | 4 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "HLA-C Antigens" by people in Profiles.
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Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection. PLoS One. 2021; 16(8):e0255608.
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HLA-C*17 in COVID-19 patients: Hints for associations with severe clinical outcome and cardiovascular risk. Immunol Lett. 2021 06; 234:44-46.
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Association between the HLA genotype and the severity of COVID-19 infection among South Asians. J Med Virol. 2021 07; 93(7):4430-4437.
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HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure. Front Immunol. 2021; 12:658570.
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A novel allele, HLA-C*15:227, identified when typing COVID-19 patients. HLA. 2021 04; 97(4):377-378.
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Population Difference in Allele Frequency of HLA-C*05 and Its Correlation with COVID-19 Mortality. Viruses. 2020 11 20; 12(11).
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COVID-19 coronavirus vaccine T cell epitope prediction analysis based on distributions of HLA class I loci (HLA-A, -B, -C) across global populations. Hum Vaccin Immunother. 2021 04 03; 17(4):1097-1108.
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Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19. J Transl Med. 2020 09 15; 18(1):352.
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[HLA genetic polymorphisms and prognosis of patients with COVID-19]. Med Intensiva (Engl Ed). 2021 Mar; 45(2):96-103.
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HLA-B*44 and C*01 Prevalence Correlates with Covid19 Spreading across Italy. Int J Mol Sci. 2020 Jul 23; 21(15).