"Macrolides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
| Descriptor ID |
D018942
|
| MeSH Number(s) |
D02.540.505 D02.540.576.500 D04.345.674.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Macrolides".
Below are MeSH descriptors whose meaning is more specific than "Macrolides".
This graph shows the total number of publications written about "Macrolides" by people in this website by year, and whether "Macrolides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 1 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 15 | 18 | 33 |
| 2018 | 17 | 6 | 23 |
| 2019 | 11 | 6 | 17 |
| 2020 | 2 | 4 | 6 |
| 2021 | 1 | 3 | 4 |
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Below are the most recent publications written about "Macrolides" by people in Profiles.
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Decreased Use of Broad-Spectrum Antibiotics During the Coronavirus Disease 2019 Epidemic in South Korea. J Infect Dis. 2021 09 17; 224(6):949-955.
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Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome Insights. Microbiol Spectr. 2021 10 31; 9(2):e0019721.
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Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors. PLoS Pathog. 2021 07; 17(7):e1009706.
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Macrolactin A as a Novel Inhibitory Agent for SARS-CoV-2 Mpro: Bioinformatics Approach. Appl Biochem Biotechnol. 2021 Oct; 193(10):3371-3394.
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Repurposing of antibiotics for clinical management of COVID-19: a narrative review. Ann Clin Microbiol Antimicrob. 2021 May 21; 20(1):37.
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Use of antibiotics in COVID-19 ICU patients. J Infect Dev Ctries. 2021 04 30; 15(4):501-505.
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Macrolides May Prevent Severe Acute Respiratory Syndrome Coronavirus 2 Entry into Cells: A Quantitative Structure Activity Relationship Study and Experimental Validation. J Chem Inf Model. 2021 04 26; 61(4):2016-2025.
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Real-World Evidence for Assessing Pharmaceutical Treatments in the Context of COVID-19. Clin Pharmacol Ther. 2021 04; 109(4):816-828.
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Inhibitors of endosomal acidification suppress SARS-CoV-2 replication and relieve viral pneumonia in hACE2 transgenic mice. Virol J. 2021 02 27; 18(1):46.
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Antiviral Bafilomycins from a Feces-Inhabiting Streptomyces sp. J Nat Prod. 2021 02 26; 84(2):537-543.