Activated Protein C Resistance
"Activated Protein C Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
| Descriptor ID |
D020016
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| MeSH Number(s) |
C15.378.100.100.037 C15.378.100.141.036 C15.378.925.050 C16.320.099.037
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Activated Protein C Resistance".
Below are MeSH descriptors whose meaning is more specific than "Activated Protein C Resistance".
This graph shows the total number of publications written about "Activated Protein C Resistance" by people in this website by year, and whether "Activated Protein C Resistance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
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Below are the most recent publications written about "Activated Protein C Resistance" by people in Profiles.
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Circulating activated protein C in thrombophilia carriers. J Thromb Thrombolysis. 2017 Apr; 43(3):361-364.
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Laboratory Testing for Activated Protein C Resistance (APCR). Methods Mol Biol. 2017; 1646:137-143.
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The predictability of factor V Leiden (FV:Q(506)) gene mutation via clotting-based diagnosis of activated protein C resistance. Clin Appl Thromb Hemost. 2004 Jul; 10(3):265-70.
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Thrombinography shows acquired resistance to activated protein C in patients with lupus anticoagulants. Thromb Haemost. 2003 Feb; 89(2):208-12.
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[Resistance to activated protein C and portal vein thrombosis: two new cases and review of the literature]. Rev Med Interne. 1999 Jul; 20(7):602-6.