"Stearoyl-CoA Desaturase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of oleoyl-CoA, A, and water from stearoyl-CoA, AH2, and oxygen where AH2 is an unspecified hydrogen donor.
| Descriptor ID |
D013230
|
| MeSH Number(s) |
D08.811.682.690.708.392.625
|
| Concept/Terms |
Stearoyl-CoA Desaturase- Stearoyl-CoA Desaturase
- Desaturase, Stearoyl-CoA
- Stearoyl CoA Desaturase
- Stearate Desaturase
- Desaturase, Stearate
- Stearyl-CoA Desaturase
- Desaturase, Stearyl-CoA
- Stearyl CoA Desaturase
- delta-9 Desaturase
- Desaturase, delta-9
- delta 9 Desaturase
|
Below are MeSH descriptors whose meaning is more general than "Stearoyl-CoA Desaturase".
Below are MeSH descriptors whose meaning is more specific than "Stearoyl-CoA Desaturase".
This graph shows the total number of publications written about "Stearoyl-CoA Desaturase" by people in this website by year, and whether "Stearoyl-CoA Desaturase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Stearoyl-CoA Desaturase" by people in Profiles.
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Co-administration of 20(S)-protopanaxatriol (g-PPT) and EGFR-TKI overcomes EGFR-TKI resistance by decreasing SCD1 induced lipid accumulation in non-small cell lung cancer. J Exp Clin Cancer Res. 2019 Mar 15; 38(1):129.
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Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway. J Exp Clin Cancer Res. 2019 Feb 21; 38(1):96.
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Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma. J Exp Clin Cancer Res. 2018 Dec 17; 37(1):318.
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Euodia daniellii Hemsl. (Bee-Bee Tree) Oil Attenuates Palmitate-Induced Lipid Accumulation and Apoptosis in Hepatocytes. Pharmacology. 2018; 101(5-6):298-308.
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GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2017 12; 37(12):2252-2259.
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Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells. Cancer Lett. 2017 10 10; 406:93-104.
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Altered fatty acid metabolism and reduced stearoyl-coenzyme a desaturase activity in asthma. Allergy. 2017 Nov; 72(11):1744-1752.
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Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ. Oncogene. 2017 08 10; 36(32):4573-4584.
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SCD1 is associated with tumor promotion, late stage and poor survival in lung adenocarcinoma. Oncotarget. 2016 Jun 28; 7(26):39970-39979.