"Substantia Nigra" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.
| Descriptor ID |
D013378
|
| MeSH Number(s) |
A08.186.211.132.659.413.656
|
| Concept/Terms |
Substantia Nigra- Substantia Nigra
- Nigra, Substantia
- Nigras, Substantia
- Substantia Nigras
|
Below are MeSH descriptors whose meaning is more general than "Substantia Nigra".
Below are MeSH descriptors whose meaning is more specific than "Substantia Nigra".
This graph shows the total number of publications written about "Substantia Nigra" by people in this website by year, and whether "Substantia Nigra" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2009 | 0 | 2 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 5 | 0 | 5 |
| 2018 | 6 | 2 | 8 |
| 2019 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Substantia Nigra" by people in Profiles.
-
Extrastriatal dopaminergic and serotonergic pathways in Parkinson's disease and in dementia with Lewy bodies: a 123I-FP-CIT SPECT study. Eur J Nucl Med Mol Imaging. 2019 Jul; 46(8):1642-1651.
-
Prodromal substantia nigra sonography undermines suggested association between substrate accumulation and the risk for GBA-related Parkinson's disease. Eur J Neurol. 2019 07; 26(7):1013-1018.
-
Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3ß-Nrf2/NF-?B Signaling Axis. Front Immunol. 2018; 9:2527.
-
Does normal substantia nigra echogenicity make a difference in Parkinson's disease diagnosis? A real clinical practice follow-up study. J Neurol. 2018 Oct; 265(10):2363-2369.
-
Reversal of dopamine-mediated firing inhibition through activation of the dopamine transporter in substantia nigra pars compacta neurons. Br J Pharmacol. 2018 09; 175(17):3534-3547.
-
Striatonigral involvement in Fabry Disease: A quantitative and volumetric Magnetic Resonance Imaging study. Parkinsonism Relat Disord. 2018 12; 57:27-32.
-
Mitochondrial alterations in Parkinson's disease human samples and cellular models. Neurochem Int. 2018 09; 118:61-72.
-
Synapsin III is a key component of a-synuclein fibrils in Lewy bodies of PD brains. Brain Pathol. 2018 11; 28(6):875-888.
-
Substantia nigra fractional anisotropy changes confirm the PD at-risk status of patients with idiopathic smell loss. Parkinsonism Relat Disord. 2018 05; 50:113-116.
-
[Mechanism of a-lipoic acid promoting iron efflux in substantia nigra cells of Parkinson's disease rats]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2018 Jan; 34(1):35-40.