X Chromosome Inactivation
"X Chromosome Inactivation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females.
| Descriptor ID |
D049951
|
| MeSH Number(s) |
G05.308.203.249.970
|
| Concept/Terms |
X Chromosome Inactivation- X Chromosome Inactivation
- Chromosome Inactivation, X
- Inactivation, X Chromosome
- Lyonization
- X-Inactivation
- X Inactivation
- Inactivation, X
- X Inactivations
|
Below are MeSH descriptors whose meaning is more general than "X Chromosome Inactivation".
Below are MeSH descriptors whose meaning is more specific than "X Chromosome Inactivation".
This graph shows the total number of publications written about "X Chromosome Inactivation" by people in this website by year, and whether "X Chromosome Inactivation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "X Chromosome Inactivation" by people in Profiles.
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B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells. Cell. 2021 04 01; 184(7):1790-1803.e17.
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Sex differences in COVID-19: candidate pathways, genetics of ACE2, and sex hormones. Am J Physiol Heart Circ Physiol. 2021 01 01; 320(1):H296-H304.
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COVID-19 and ACE2 in the Liver and Gastrointestinal Tract: Putative Biological Explanations of Sexual Dimorphism. Gastroenterology. 2020 10; 159(4):1620-1621.
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Aberrant X chromosome skewing and acquired clonal hematopoiesis in adult-onset common variable immunodeficiency. JCI Insight. 2019 07 25; 4(14).
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Involvement of X-chromosome Reactivation in Augmenting Cancer Testis Antigens Expression: A Hypothesis. Curr Med Sci. 2018 Feb; 38(1):19-25.
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The D313Y variant in the GLA gene - no evidence of a pathogenic role in Fabry disease. Scand J Clin Lab Invest. 2017 Dec; 77(8):617-621.
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Haemophilia A: the consequences of de novo mutations. Two case reports. Blood Transfus. 2018 07; 16(4):392-393.
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A sibship with duplication of Xq28 inherited from the mother; genomic characterization and clinical outcomes. BMC Med Genet. 2017 03 17; 18(1):30.
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A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):14366-14371.
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Molecular and clinical characterization of a small duplication Xp in a human female with psychiatric disorders. J Genet. 2011 Dec; 90(3):473-7.