"Rats, Sprague-Dawley" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
| Descriptor ID |
D017207
|
| MeSH Number(s) |
B01.050.150.900.649.313.992.635.505.700.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Rats, Sprague-Dawley".
Below are MeSH descriptors whose meaning is more specific than "Rats, Sprague-Dawley".
This graph shows the total number of publications written about "Rats, Sprague-Dawley" by people in this website by year, and whether "Rats, Sprague-Dawley" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 9 | 9 |
| 2006 | 0 | 6 | 6 |
| 2007 | 0 | 7 | 7 |
| 2008 | 0 | 5 | 5 |
| 2009 | 0 | 6 | 6 |
| 2010 | 0 | 11 | 11 |
| 2011 | 0 | 11 | 11 |
| 2012 | 0 | 8 | 8 |
| 2013 | 0 | 4 | 4 |
| 2014 | 0 | 7 | 7 |
| 2015 | 0 | 8 | 8 |
| 2016 | 0 | 11 | 11 |
| 2017 | 0 | 182 | 182 |
| 2018 | 0 | 167 | 167 |
| 2019 | 0 | 68 | 68 |
| 2020 | 0 | 4 | 4 |
| 2021 | 0 | 6 | 6 |
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Below are the most recent publications written about "Rats, Sprague-Dawley" by people in Profiles.
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The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract. Emerg Microbes Infect. 2021 Dec; 10(1):481-492.
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COVID19-associated cardiomyocyte dysfunction, arrhythmias and the effect of Canakinumab. PLoS One. 2021; 16(8):e0255976.
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Quantitative HPLC-MS/MS determination of Nuc, the active metabolite of remdesivir, and its pharmacokinetics in rat. Anal Bioanal Chem. 2021 Sep; 413(23):5811-5820.
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Discovery and evolution of 12N-substituted aloperine derivatives as anti-SARS-CoV-2 agents through targeting late entry stage. Bioorg Chem. 2021 10; 115:105196.
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Bioanalysis of niclosamide in plasma using liquid chromatography-tandem mass and application to pharmacokinetics in rats and dogs. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 01; 1179:122862.
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Food Enrichment with Glycyrrhiza glabra Extract Suppresses ACE2 mRNA and Protein Expression in Rats-Possible Implications for COVID-19. Nutrients. 2021 Jul 06; 13(7).
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N-acylethanolamine regulation of TLR3-induced hyperthermia and neuroinflammatory gene expression: A role for PPARa. J Neuroimmunol. 2021 09 15; 358:577654.
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ELV-N32 and RvD6 isomer decrease pro-inflammatory cytokines, senescence programming, ACE2 and SARS-CoV-2-spike protein RBD binding in injured cornea. Sci Rep. 2021 06 17; 11(1):12787.
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Non-clinical safety profile and pharmacodynamics of two formulations of the anti-sepsis drug candidate Rejuveinix (RJX). Biomed Pharmacother. 2021 Sep; 141:111823.
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Ciclesonide activates glucocorticoid signaling in neonatal rat lung but does not trigger adverse effects in the cortex and cerebellum. Neurobiol Dis. 2021 08; 156:105422.