"Connexins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
| Descriptor ID |
D017630
|
| MeSH Number(s) |
D12.776.543.585.250
|
| Concept/Terms |
Connexins- Connexins
- Gap Junction Protein
- Junction Protein, Gap
- Gap Junction Proteins
- Junction Proteins, Gap
- Gap Junction Channel Proteins
|
Below are MeSH descriptors whose meaning is more general than "Connexins".
Below are MeSH descriptors whose meaning is more specific than "Connexins".
This graph shows the total number of publications written about "Connexins" by people in this website by year, and whether "Connexins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 5 | 3 | 8 |
| 2018 | 4 | 1 | 5 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Connexins" by people in Profiles.
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Consideration of Pannexin 1 channels in COVID-19 pathology and treatment. Am J Physiol Lung Cell Mol Physiol. 2020 07 01; 319(1):L121-L125.
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Keratoderma-Deafness-Mucocutaneous Syndrome Associated with Phe142Leu in the GJB2 Gene. Acta Derm Venereol. 2019 Nov 01; 99(12):1192-1194.
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Russian 'CRISPR-baby' scientist has started editing genes in human eggs with goal of altering deaf gene. Nature. 2019 10; 574(7779):465-466.
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Connexin 40 regulates lung endothelial permeability in acute lung injury via the ROCK1-MYPT1- MLC20 pathway. Am J Physiol Lung Cell Mol Physiol. 2019 01 01; 316(1):L35-L44.
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Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury. Antioxid Redox Signal. 2019 04 20; 30(12):1521-1538.
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The Transcription Factor ETV1 Induces Atrial Remodeling and Arrhythmia. Circ Res. 2018 08 17; 123(5):550-563.
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Targeting different domains of gap junction protein to control malignant glioma. Neuro Oncol. 2018 06 18; 20(7):885-896.
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Spectrum of GJB2 gene variants in Indian children with non-syndromic hearing loss. Indian J Med Res. 2018 06; 147(6):615-618.
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The connexin 46 mutant (V44M) impairs gap junction function causing congenital cataract. J Genet. 2017 Dec; 96(6):969-976.
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The endothelium in hypoxic pulmonary vasoconstriction. J Appl Physiol (1985). 2017 12 01; 123(6):1635-1646.