"Tuftsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
| Descriptor ID |
D014405
|
| MeSH Number(s) |
D12.644.456.840 D12.644.541.500.650.750 D12.776.124.486.485.397.500 D12.776.124.486.485.680.650.750 D12.776.124.790.651.397.500 D12.776.124.790.651.680.650.750 D12.776.377.715.548.397.500 D12.776.377.715.548.680.650.750
|
| Concept/Terms |
Tuftsin- Tuftsin
- L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine
- Taftsin
- L-Thr-L-Lys-L-Pro-L-Arg
|
Below are MeSH descriptors whose meaning is more general than "Tuftsin".
Below are MeSH descriptors whose meaning is more specific than "Tuftsin".
This graph shows the total number of publications written about "Tuftsin" by people in this website by year, and whether "Tuftsin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tuftsin" by people in Profiles.
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Helminth-Related Tuftsin-Phosphorylcholine Compound and its Interplay with Autoimmune Diseases. Isr Med Assoc J. 2019 Mar; 21(3):158-162.
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Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis. PLoS One. 2018; 13(8):e0200615.
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Tuftsin-phosphorylcholine (TPC) equally effective to methylprednisolone in ameliorating lupus nephritis in a mice model. Clin Exp Immunol. 2018 08; 193(2):160-166.
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A phase trial of the oral Lactobacillus casei vaccine polarizes Th2 cell immunity against transmissible gastroenteritis coronavirus infection. Appl Microbiol Biotechnol. 2016 Sep; 100(17):7457-69.
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Up-regulation of MDP and tuftsin gene expression in Th1 and Th17 cells as an adjuvant for an oral Lactobacillus casei vaccine against anti-transmissible gastroenteritis virus. Appl Microbiol Biotechnol. 2014 Oct; 98(19):8301-12.