"Genes, pol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA sequences that form the coding region for retroviral enzymes including reverse transcriptase, protease, and endonuclease/integrase. "pol" is short for polymerase, the enzyme class of reverse transcriptase.
| Descriptor ID |
D015751
|
| MeSH Number(s) |
G05.360.340.024.340.364.875.667 G05.360.340.358.024.875.667 G05.360.340.358.840.500.667
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Genes, pol".
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Genome [G05.360.340]
- Genome Components [G05.360.340.024]
- Genes [G05.360.340.024.340]
- Genes, Microbial [G05.360.340.024.340.364]
- Genes, Viral [G05.360.340.024.340.364.875]
- Genes, pol [G05.360.340.024.340.364.875.667]
- Genome, Microbial [G05.360.340.358]
- Genes, Microbial [G05.360.340.358.024]
- Genes, Viral [G05.360.340.358.024.875]
- Genes, pol [G05.360.340.358.024.875.667]
- Genome, Viral [G05.360.340.358.840]
- Genes, Viral [G05.360.340.358.840.500]
- Genes, pol [G05.360.340.358.840.500.667]
Below are MeSH descriptors whose meaning is more specific than "Genes, pol".
This graph shows the total number of publications written about "Genes, pol" by people in this website by year, and whether "Genes, pol" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2012 | 1 | 3 | 4 |
| 2017 | 0 | 2 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Genes, pol" by people in Profiles.
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MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors. Viruses. 2019 08 30; 11(9).
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Diversity of HIV-1 genotypes and high prevalence of pretreatment drug resistance in newly diagnosed HIV-infected patients in Shanghai, China. BMC Infect Dis. 2019 Apr 08; 19(1):313.
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Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targeting the HIV reservoir. BMC Biol. 2018 07 11; 16(1):75.
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Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults. PLoS One. 2018; 13(1):e0190438.
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High levels of virological failure with major genotypic resistance mutations in HIV-1-infected children after 5 years of care according to WHO-recommended 1st-line and 2nd-line antiretroviral regimens in the Central African Republic: A cross-sectional study. Medicine (Baltimore). 2017 Mar; 96(10):e6282.
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HIV-1 genetic diversity and transmitted drug resistance frequency among Iranian treatment-naive, sexually infected individuals. Arch Virol. 2017 Jun; 162(6):1477-1485.
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Molecular characterization of human coronaviruses and their circulation dynamics in Kenya, 2009-2012. Virol J. 2016 Feb 01; 13:18.
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Mutations in HIV-1 gag and pol compensate for the loss of viral fitness caused by a highly mutated protease. Antimicrob Agents Chemother. 2012 Aug; 56(8):4320-30.
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Epidemiology of coronavirus-associated respiratory tract infections and the role of rapid diagnostic tests: a prospective study. Hong Kong Med J. 2012 Feb; 18 Suppl 2:22-4.
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Wild animal surveillance for coronavirus HKU1 and potential variants of other coronaviruses. Hong Kong Med J. 2012 Feb; 18 Suppl 2:25-6.