"Protamines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
| Descriptor ID |
D011479
|
| MeSH Number(s) |
D12.776.660.750 D12.776.664.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protamines".
Below are MeSH descriptors whose meaning is more specific than "Protamines".
This graph shows the total number of publications written about "Protamines" by people in this website by year, and whether "Protamines" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Protamines" by people in Profiles.
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Protamine reversal of heparin: a fishy practice? Europace. 2019 06 01; 21(6):840-841.
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Cytological and molecular aspects of the ageing sperm. Hum Reprod. 2019 02 01; 34(2):218-227.
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Protamine, is something fishy about it? The spectre of anaphylaxis continues. J Cardiothorac Vasc Anesth. 2019 02; 33(2):487-488.
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Advances in Heparins and Related Research. An Epilogue. Molecules. 2018 Feb 12; 23(2).
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Forensic aspects of homicides by insulin overdose. Forensic Sci Int. 2017 Sep; 278:9-15.
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Heparin-like effect resistant to protamine in a child with haemorrhagic shock. Do we need heparinase? Blood Transfus. 2018 07; 16(4):394-396.
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Perioperative Coagulation Management of a Hemophilia A Patient During Cardiac Surgery. Semin Cardiothorac Vasc Anesth. 2017 Dec; 21(4):312-320.
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Mast cells activation contribute to small intestinal ischemia reperfusion induced acute lung injury in rats. Injury. 2012 Aug; 43(8):1250-6.
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Safety and benefits of protamine administration to revert anticoagulation soon after coronary angioplasty. A meta-analysis. J Thromb Thrombolysis. 2010 Nov; 30(4):452-8.