Peptide Elongation Factor 1
"Peptide Elongation Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
| Descriptor ID |
D020648
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| MeSH Number(s) |
D08.811.277.040.330.300.100.101 D12.776.157.325.150.101 D12.776.835.700.350.101
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peptide Elongation Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Peptide Elongation Factor 1".
This graph shows the total number of publications written about "Peptide Elongation Factor 1" by people in this website by year, and whether "Peptide Elongation Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptide Elongation Factor 1" by people in Profiles.
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High-level expression of the monomeric SARS-CoV-2 S protein RBD 320-537 in stably transfected CHO cells by the EEF1A1-based plasmid vector. PLoS One. 2021; 16(2):e0242890.
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Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A. Science. 2021 02 26; 371(6532):926-931.
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Postmortem proteomics to discover biomarkers for forensic PMI estimation. Int J Legal Med. 2019 May; 133(3):899-908.
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The current Indian epidemic of superficial dermatophytosis due to Trichophyton mentagrophytes-A molecular study. Mycoses. 2019 Apr; 62(4):336-356.
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Fusarium metavorans sp. nov.: The frequent opportunist 'FSSC6'. Med Mycol. 2018 Apr 01; 56(suppl_1):144-152.
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EF1A interacting with nucleocapsid protein of transmissible gastroenteritis coronavirus and plays a role in virus replication. Vet Microbiol. 2014 Aug 27; 172(3-4):443-8.
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The nucleocapsid protein of severe acute respiratory syndrome coronavirus inhibits cell cytokinesis and proliferation by interacting with translation elongation factor 1alpha. J Virol. 2008 Jul; 82(14):6962-71.