"Mutagenesis, Insertional" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
Descriptor ID |
D016254
|
MeSH Number(s) |
E05.393.420.601.550 G05.365.590.575 G05.558.550
|
Concept/Terms |
Sequence Insertion- Sequence Insertion
- Insertion, Sequence
- Insertions, Sequence
- Sequence Insertions
Gene Insertion- Gene Insertion
- Gene Insertions
- Insertion, Gene
- Insertions, Gene
Insertion Mutation- Insertion Mutation
- Insertion Mutations
- Mutation, Insertion
- Mutations, Insertion
Insertional Activation- Insertional Activation
- Activation, Insertional
- Activations, Insertional
- Insertional Activations
|
Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Insertional".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Insertional".
This graph shows the total number of publications written about "Mutagenesis, Insertional" by people in this website by year, and whether "Mutagenesis, Insertional" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1995 | 0 | 2 | 2 |
2001 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2017 | 4 | 8 | 12 |
2018 | 5 | 5 | 10 |
2019 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Mutagenesis, Insertional" by people in Profiles.
-
Angiotensin-converting enzyme-1 gene insertion/deletion polymorphism may be associated with COVID-19 clinical severity: a prospective cohort study. Ann Saudi Med. 2021 May-Jun; 41(3):141-146.
-
Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses. Proc Natl Acad Sci U S A. 2020 06 30; 117(26):15193-15199.
-
A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein. Curr Biol. 2020 06 08; 30(11):2196-2203.e3.
-
Long-term Prognostic Impact of Chromosome Abnormalities in Clear Cell Renal Cell Carcinoma. Anticancer Res. 2019 Jun; 39(6):2757-2765.
-
Biological characterization and pathogenicity of a newly isolated Chinese highly virulent genotype GIIa porcine epidemic diarrhea virus strain. Arch Virol. 2019 May; 164(5):1287-1295.
-
A practical random mutagenesis system for Ralstonia solanacearum strains causing bacterial wilt of Pogostemon cablin using Tn5 transposon. World J Microbiol Biotechnol. 2018 Dec 18; 35(1):7.
-
The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis. mSphere. 2018 12 12; 3(6).
-
Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks. Nature. 2018 12; 564(7735):287-290.
-
Lymphomagenic properties of a HIV p17 variant derived from a splenic marginal zone lymphoma occurred in a HIV-infected patient. Hematol Oncol. 2019 Apr; 37(2):176-184.
-
Role of the acquisition of a type 3 secretion system in the emergence of novel pathogenic strains of Xanthomonas. Mol Plant Pathol. 2019 01; 20(1):33-50.