"Prion Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
| Descriptor ID |
D017096
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| MeSH Number(s) |
C10.228.228.800 C10.574.843
|
| Concept/Terms |
Prion Diseases- Prion Diseases
- Spongiform Encephalopathies, Transmissible
- Encephalopathies, Transmissible Spongiform
- Encephalopathy, Transmissible Spongiform
- Spongiform Encephalopathy, Transmissible
- Transmissible Spongiform Encephalopathy
- Dementias, Transmissible
- Dementia, Transmissible
- Transmissible Dementia
- Transmissible Dementias
- Prion-Induced Disorders
- Prion Protein Diseases
- Prion Protein Disease
- Prion-Induced Disorder
- Disorder, Prion-Induced
- Disorders, Prion-Induced
- Prion Induced Disorder
- Prion Disease
- Prion-Associated Disorders
- Transmissible Spongiform Encephalopathies
- Encephalopathies, Spongiform, Transmissible
|
Below are MeSH descriptors whose meaning is more general than "Prion Diseases".
Below are MeSH descriptors whose meaning is more specific than "Prion Diseases".
This graph shows the total number of publications written about "Prion Diseases" by people in this website by year, and whether "Prion Diseases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 3 | 0 | 3 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Prion Diseases" by people in Profiles.
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Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December 2020. Commun Dis Intell (2018). 2021 Jul 22; 45.
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Plasma total prion protein as a potential biomarker for neurodegenerative dementia: diagnostic accuracy in the spectrum of prion diseases. Neuropathol Appl Neurobiol. 2020 04; 46(3):240-254.
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Recent advances on the molecular pathogenesis of prion diseases. Brain Pathol. 2019 03; 29(2):245-247.
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Sporadic Fatal Insomnia in Europe: Phenotypic Features and Diagnostic Challenges. Ann Neurol. 2018 09; 84(3):347-360.
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A Practical Primer on Prion Pathology. J Neuropathol Exp Neurol. 2018 05 01; 77(5):346-352.
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Infectious prions do not induce Aß deposition in an in vivo seeding model. Acta Neuropathol. 2018 06; 135(6):965-967.
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Mass Confusion. J Hosp Med. 2017 09; 12(9):750-754.
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Diverse functions of the prion protein - Does proteolytic processing hold the key? Biochim Biophys Acta Mol Cell Res. 2017 Nov; 1864(11 Pt B):2128-2137.
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Role of metal ions in aggregation of intrinsically disordered proteins in neurodegenerative diseases. Metallomics. 2011 Nov; 3(11):1163-80.
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Spongiform degeneration induced by neuropathogenic murine coronavirus infection. Pathol Int. 2011 Apr; 61(4):184-91.