"Troponin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
| Descriptor ID |
D019210
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| MeSH Number(s) |
D05.500.945.925 D05.750.078.730.825.925 D12.776.210.500.910.925 D12.776.220.525.825.925
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Troponin I".
Below are MeSH descriptors whose meaning is more specific than "Troponin I".
This graph shows the total number of publications written about "Troponin I" by people in this website by year, and whether "Troponin I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 3 | 1 | 4 |
| 2016 | 5 | 1 | 6 |
| 2017 | 31 | 15 | 46 |
| 2018 | 19 | 19 | 38 |
| 2019 | 10 | 1 | 11 |
| 2020 | 19 | 20 | 39 |
| 2021 | 5 | 11 | 16 |
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Below are the most recent publications written about "Troponin I" by people in Profiles.
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Cardiac biomarkers, cardiac injury, and comorbidities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis. Immun Inflamm Dis. 2021 12; 9(4):1071-1100.
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Mechanisms of Myocardial Injury in COVID-19. Clin Chem. 2021 08 05; 67(8):1044-1046.
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Troponin elevation in COVID-19 patients: An important stratification biomarker with still some open questions. Int J Cardiol. 2021 10 15; 341:107-109.
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Prognostic significance of cardiac injury in COVID-19 patients with and without coronary artery disease. Coron Artery Dis. 2021 08 01; 32(5):359-366.
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Cardiac biomarkers and COVID-19: A systematic review and meta-analysis. J Infect Public Health. 2021 Sep; 14(9):1191-1197.
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Can we predict the severe course of COVID-19 - a systematic review and meta-analysis of indicators of clinical outcome? PLoS One. 2021; 16(7):e0255154.
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The role of antibody-based troponin detection in cardiovascular disease: A critical assessment. J Immunol Methods. 2021 10; 497:113108.
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Evolution of Management and Outcomes of Patients with Myocardial Injury During the COVID-19 Pandemic. Am J Cardiol. 2021 10 15; 157:42-47.
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Longitudinal monitoring of laboratory markers characterizes hospitalized and ambulatory COVID-19 patients. Sci Rep. 2021 07 14; 11(1):14471.
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Predictive value of cardiac markers in the prognosis of COVID-19 in children. Am J Emerg Med. 2021 Oct; 48:307-311.