"Germinal Center" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T-LYMPHOCYTES, HELPER-INDUCER) are stimulated to generate memory cells.
| Descriptor ID |
D018858
|
| MeSH Number(s) |
A10.549.400.500 A15.382.520.604.412.500
|
| Concept/Terms |
Germinal Center- Germinal Center
- Center, Germinal
- Centers, Germinal
- Germinal Centers
|
Below are MeSH descriptors whose meaning is more general than "Germinal Center".
Below are MeSH descriptors whose meaning is more specific than "Germinal Center".
This graph shows the total number of publications written about "Germinal Center" by people in this website by year, and whether "Germinal Center" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2017 | 9 | 7 | 16 |
| 2018 | 10 | 7 | 17 |
| 2019 | 4 | 3 | 7 |
| 2020 | 2 | 0 | 2 |
| 2021 | 3 | 3 | 6 |
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Below are the most recent publications written about "Germinal Center" by people in Profiles.
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A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants. Immunity. 2021 09 14; 54(9):2159-2166.e6.
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AID and APOBECs as Multifaceted Intrinsic Virus-Restricting Factors: Emerging Concepts in the Light of COVID-19. Front Immunol. 2021; 12:690416.
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SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses. Nature. 2021 08; 596(7870):109-113.
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Optimized immunofluorescence staining protocol for imaging germinal centers in secondary lymphoid tissues of vaccinated mice. STAR Protoc. 2021 09 17; 2(3):100499.
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Original Antigenic Sin: the Downside of Immunological Memory and Implications for COVID-19. mSphere. 2021 03 10; 6(2).
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Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity. Adv Healthc Mater. 2021 05; 10(10):e2002142.
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Transcriptional and Metabolic Control of Memory B Cells and Plasma Cells. Annu Rev Immunol. 2021 04 26; 39:345-368.
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An Immunological Perspective: What Happened to Pregnant Women After Recovering From COVID-19? Front Immunol. 2021; 12:631044.
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Maturation and persistence of the anti-SARS-CoV-2 memory B cell response. Cell. 2021 03 04; 184(5):1201-1213.e14.
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SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques. Nat Commun. 2021 01 22; 12(1):541.