Tissue Inhibitor of Metalloproteinase-1
"Tissue Inhibitor of Metalloproteinase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro.
Descriptor ID |
D019715
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MeSH Number(s) |
D12.776.645.875.450
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tissue Inhibitor of Metalloproteinase-1".
Below are MeSH descriptors whose meaning is more specific than "Tissue Inhibitor of Metalloproteinase-1".
This graph shows the total number of publications written about "Tissue Inhibitor of Metalloproteinase-1" by people in this website by year, and whether "Tissue Inhibitor of Metalloproteinase-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 4 | 2 | 6 |
2018 | 1 | 5 | 6 |
2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Tissue Inhibitor of Metalloproteinase-1" by people in Profiles.
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Structural characterisation of inhibitory and non-inhibitory MMP-9-TIMP-1 complexes and implications for regulatory mechanisms of MMP-9. Sci Rep. 2021 06 28; 11(1):13376.
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Animal Models of Steatosis (NAFLD) and Steatohepatitis (NASH) Exhibit Hepatic Lobe-Specific Gelatinases Activity and Oxidative Stress. Can J Gastroenterol Hepatol. 2019; 2019:5413461.
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A Randomized, Controlled Trial of Vitamin D Supplementation on Cardiovascular Risk Factors, Hormones, and Liver Markers in Women with Polycystic Ovary Syndrome. Nutrients. 2019 Jan 17; 11(1).
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Validation of Serum Test for Advanced Liver Fibrosis in Patients With Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2019 08; 17(9):1867-1876.e3.
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Soluble stroma-related biomarkers of pancreatic cancer. EMBO Mol Med. 2018 08; 10(8).
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Plasma levels of heart failure biomarkers are primarily a reflection of extracardiac production. Theranostics. 2018; 8(15):4155-4169.
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Effects of treatment with Maraviroc a CCR5 inhibitor on a human hepatic stellate cell line. J Cell Physiol. 2018 08; 233(8):6224-6231.
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ß-Alanine mediated inhibition of PTHR1suppresses the proliferation, invasion and tumorigenesis in metastatic human osteosarcoma U2OS cells. Int J Biol Macromol. 2018 May; 111:1255-1263.
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Inhibition of Fibroblast Activation Protein Restores a Balanced Extracellular Matrix and Reduces Fibrosis in Crohn's Disease Strictures Ex Vivo. Inflamm Bowel Dis. 2018 01 18; 24(2):332-345.
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Dampness-Heat Accelerates DMBA-Induced Mammary Tumors in Rats. Chin J Integr Med. 2018 Oct; 24(10):758-762.