"Caspase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.
| Descriptor ID |
D020170
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.550.100 D08.811.277.656.300.200.126.550.100 D12.644.360.075.405.550.100 D12.776.476.075.405.550.100
|
| Concept/Terms |
Caspase 1- Caspase 1
- Interleukin-1beta Converting Enzyme
- Converting Enzyme, Interleukin-1beta
- Interleukin 1beta Converting Enzyme
- ICE Protease
- IL1BC Enzyme
- IL-1 beta Convertase
- Convertase, IL-1 beta
- IL 1 beta Convertase
- beta Convertase, IL-1
- CASP1 Caspase
- Caspase, CASP1
- Interleukin-1 Converting Enzyme
- Converting Enzyme, Interleukin-1
- Interleukin 1 Converting Enzyme
- IL-1 beta-Converting Enzyme
- IL 1 beta Converting Enzyme
- beta-Converting Enzyme, IL-1
Procaspase-1- Procaspase-1
- Procaspase 1
- Pro-Caspase-1
- Pro Caspase 1
|
Below are MeSH descriptors whose meaning is more general than "Caspase 1".
Below are MeSH descriptors whose meaning is more specific than "Caspase 1".
This graph shows the total number of publications written about "Caspase 1" by people in this website by year, and whether "Caspase 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 17 | 19 |
| 2018 | 5 | 12 | 17 |
| 2019 | 0 | 5 | 5 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 1" by people in Profiles.
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Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections. Cell Rep. 2021 08 24; 36(8):109614.
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SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage. EMBO J. 2021 09 15; 40(18):e108249.
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Caspases and therapeutic potential of caspase inhibitors in moderate-severe SARS-CoV-2 infection and long COVID. Allergy. 2022 01; 77(1):118-129.
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Activation of Interleukin-1ß Release and Pyroptosis by Transmissible Gastroenteritis Virus Is Dependent on the NOD-Like Receptor Protein 3 Inflammasome in Porcine Intestinal Epithelial Cell Line. Viral Immunol. 2021 Jul-Aug; 34(6):401-409.
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Inflammasome formation in the lungs of patients with fatal COVID-19. Inflamm Res. 2021 Jan; 70(1):7-10.
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The Inflammasome in Times of COVID-19. Front Immunol. 2020; 11:583373.
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Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine. Mol Med. 2020 07 08; 26(1):69.
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Inflammasome activation and pyroptosis in lymphopenic liver patients with COVID-19. J Hepatol. 2020 11; 73(5):1258-1262.
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The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis. Front Immunol. 2019; 10:1566.
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Polysaccharide from Scutellaria baicalensis Georgi ameliorates colitis via suppressing NF-?B signaling and NLRP3 inflammasome activation. Int J Biol Macromol. 2019 Jul 01; 132:393-405.