STAT5 Transcription Factor
"STAT5 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
| Descriptor ID |
D050799
|
| MeSH Number(s) |
D12.644.360.024.342.500 D12.776.157.057.186.500 D12.776.476.024.430.500 D12.776.930.840.500
|
| Concept/Terms |
STAT5 Transcription Factor- STAT5 Transcription Factor
- Factor, STAT5 Transcription
- Transcription Factor, STAT5
- STAT5 Protein
- Signal Transducer and Activator of Transcription 5
STAT5b Transcription Factor- STAT5b Transcription Factor
- Transcription Factor, STAT5b
- STAT5beta Protein
- STAT5b Protein
- Signal Transducer and Activator of Transcription 5B
STAT5a Transcription Factor- STAT5a Transcription Factor
- Transcription Factor, STAT5a
- Mammary Gland Factor
- Signal Transducer and Activator of Transcription 5A
- STAT5alpha Protein
- STAT5a Protein
- Mammary Gland-Specific Nuclear Factor
- Mammary Gland Specific Nuclear Factor
|
Below are MeSH descriptors whose meaning is more general than "STAT5 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "STAT5 Transcription Factor".
This graph shows the total number of publications written about "STAT5 Transcription Factor" by people in this website by year, and whether "STAT5 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 6 | 7 |
| 2018 | 0 | 5 | 5 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "STAT5 Transcription Factor" by people in Profiles.
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Activation of the SARS-CoV-2 Receptor Ace2 through JAK/STAT-Dependent Enhancers during Pregnancy. Cell Rep. 2020 09 29; 32(13):108199.
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The inhibition of IL-2/IL-2R gives rise to CD8+ T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia. Cell Death Dis. 2020 06 08; 11(6):429.
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Identifying crucial genes for prognosis in septic patients: Gene integration study based on PRISMA guidelines. Medicine (Baltimore). 2019 Aug; 98(33):e16807.
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Low-dose IL-2 expands CD4+ regulatory T cells with a suppressive function in vitro via the STAT5-dependent pathway in patients with chronic kidney diseases. Ren Fail. 2018 Nov; 40(1):280-288.
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RITA induces apoptosis in p53-null K562 leukemia cells by inhibiting STAT5, Akt, and NF-?B signaling pathways. Anticancer Drugs. 2018 10; 29(9):847-853.
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CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production. Cell Death Dis. 2018 09 05; 9(9):905.
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Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. Nat Commun. 2018 03 15; 9(1):1095.
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Decreased CD122 on CD56dim NK associated with its impairment in asymptomatic chronic HBV carriers with high levels of HBV DNA, HBsAg and HBeAg. Life Sci. 2018 Feb 15; 195:53-60.
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IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion. JCI Insight. 2017 11 16; 2(22).
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PLC?-dependent mTOR signalling controls IL-7-mediated early B cell development. Nat Commun. 2017 11 13; 8(1):1457.