"Enzyme Assays" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Methods used to measure the relative activity of a specific enzyme or its concentration in solution. Typically an enzyme substrate is added to a buffer solution containing enzyme and the rate of conversion of substrate to product is measured under controlled conditions. Many classical enzymatic assay methods involve the use of synthetic colorimetric substrates and measuring the reaction rates using a spectrophotometer.
| Descriptor ID |
D057075
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| MeSH Number(s) |
E05.196.427
|
| Concept/Terms |
Enzyme Assays- Enzyme Assays
- Assay, Enzyme
- Assays, Enzyme
- Enzyme Assay
- Enzymatic Assays
- Assay, Enzymatic
- Assays, Enzymatic
- Enzymatic Assay
Indirect Enzyme Assays- Indirect Enzyme Assays
- Assay, Indirect Enzyme
- Assays, Indirect Enzyme
- Enzyme Assay, Indirect
- Enzyme Assays, Indirect
- Indirect Enzyme Assay
- Indirect Enzymatic Assays
- Assay, Indirect Enzymatic
- Assays, Indirect Enzymatic
- Enzymatic Assay, Indirect
- Enzymatic Assays, Indirect
- Indirect Enzymatic Assay
|
Below are MeSH descriptors whose meaning is more general than "Enzyme Assays".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Assays".
This graph shows the total number of publications written about "Enzyme Assays" by people in this website by year, and whether "Enzyme Assays" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 6 | 7 | 13 |
| 2018 | 3 | 3 | 6 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 8 | 8 |
To return to the timeline, click here.
Below are the most recent publications written about "Enzyme Assays" by people in Profiles.
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Iterated Virtual Screening-Assisted Antiviral and Enzyme Inhibition Assays Reveal the Discovery of Novel Promising Anti-SARS-CoV-2 with Dual Activity. Int J Mol Sci. 2021 Aug 22; 22(16).
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OFF-State-Specific Inhibition of the Proprotein Convertase Furin. ACS Chem Biol. 2021 09 17; 16(9):1692-1700.
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CuCl2-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling-cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors. Bioorg Chem. 2021 10; 115:105265.
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Enzymatic Assays to Explore Viral mRNA Capping Machinery. Chembiochem. 2021 12 02; 22(23):3236-3253.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp12/7/8 RNA-dependent RNA polymerase. Biochem J. 2021 07 16; 478(13):2425-2443.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease. Biochem J. 2021 07 16; 478(13):2465-2479.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease. Biochem J. 2021 07 16; 478(13):2517-2531.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease. Biochem J. 2021 07 16; 478(13):2445-2464.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease. Biochem J. 2021 07 16; 478(13):2499-2515.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase. Biochem J. 2021 07 16; 478(13):2481-2497.