"Claudin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.
| Descriptor ID |
D062445
|
| MeSH Number(s) |
D12.776.543.940.200.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Claudin-1".
Below are MeSH descriptors whose meaning is more specific than "Claudin-1".
This graph shows the total number of publications written about "Claudin-1" by people in this website by year, and whether "Claudin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2017 | 2 | 3 | 5 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Claudin-1" by people in Profiles.
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Disclosure of Misattributed Paternity. Pediatrics. 2019 06; 143(6).
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Expression Cloning of Host Factors Required for the HCV Replication Cycle. Methods Mol Biol. 2019; 1911:169-182.
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H3N2 influenza virus infection enhances oncostatin M expression in human nasal epithelium. Exp Cell Res. 2018 10 15; 371(2):322-329.
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Dietary l-arginine inhibits intestinal Clostridium perfringens colonisation and attenuates intestinal mucosal injury in broiler chickens. Br J Nutr. 2017 Sep; 118(5):321-332.
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Sec24C-Dependent Transport of Claudin-1 Regulates Hepatitis C Virus Entry. J Virol. 2017 09 15; 91(18).
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Effects of Kluyveromyces marxianus supplementation on immune responses, intestinal structure and microbiota in broiler chickens. PLoS One. 2017; 12(7):e0180884.
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Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape. Gut. 2018 04; 67(4):736-745.
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Secretions of Bifidobacterium infantis and Lactobacillus acidophilus Protect Intestinal Epithelial Barrier Function. J Pediatr Gastroenterol Nutr. 2017 03; 64(3):404-412.
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Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody. Nat Biotechnol. 2015 May; 33(5):549-554.