Sialic Acid Binding Ig-like Lectin 1
"Sialic Acid Binding Ig-like Lectin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sialic acid binding lectin that was originally identified as an adhesion molecule for inflammatory MACROPHAGES and activated MONOCYTES. This protein is the largest known siglec subtype and contains 16 immunoglobulin C2-set domains. It plays a role in cell to cell interactions and interactions with bacteria.
| Descriptor ID |
D063267
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| MeSH Number(s) |
D12.776.503.921.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sialic Acid Binding Ig-like Lectin 1".
Below are MeSH descriptors whose meaning is more specific than "Sialic Acid Binding Ig-like Lectin 1".
This graph shows the total number of publications written about "Sialic Acid Binding Ig-like Lectin 1" by people in this website by year, and whether "Sialic Acid Binding Ig-like Lectin 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 3 | 1 | 4 |
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Below are the most recent publications written about "Sialic Acid Binding Ig-like Lectin 1" by people in Profiles.
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Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies. Nature. 2021 10; 598(7880):342-347.
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CD169 Defines Activated CD14+ Monocytes With Enhanced CD8+ T Cell Activation Capacity. Front Immunol. 2021; 12:697840.
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Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV-2 infection. Cell Rep Med. 2021 06 15; 2(6):100291.
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CD169/SIGLEC1 is expressed on circulating monocytes in COVID-19 and expression levels are associated with disease severity. Infection. 2021 Aug; 49(4):757-762.
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Monocyte CD169 Expression as a Biomarker in the Early Diagnosis of Coronavirus Disease 2019. J Infect Dis. 2021 02 24; 223(4):562-567.
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CD169 and CD64 could help differentiate bacterial from CoVID-19 or other viral infections in the Emergency Department. Cytometry A. 2021 05; 99(5):435-445.
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Monocyte CD169 expression in COVID-19 patients upon intensive care unit admission. Cytometry A. 2021 05; 99(5):466-471.
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A distinct innate immune signature marks progression from mild to severe COVID-19. Cell Rep Med. 2021 01 19; 2(1):100166.
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Dendritic Cells From the Cervical Mucosa Capture and Transfer HIV-1 via Siglec-1. Front Immunol. 2019; 10:825.
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B Cell-Mediated Maintenance of Cluster of Differentiation 169-Positive Cells Is Critical for Liver Regeneration. Hepatology. 2018 12; 68(6):2348-2361.