"Interleukin-27" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterodimeric cytokine composed of the IL-27p28 and EBI3 subunits. It is produced primarily by antigen-presenting cells after stimulation by microbial products or inflammatory mediators.
| Descriptor ID |
D064094
|
| MeSH Number(s) |
D12.644.276.374.465.800 D12.776.467.374.465.800 D23.529.374.465.600
|
| Concept/Terms |
Interleukin-27- Interleukin-27
- Interleukin 27
- IL-17D
- IL27
- IL-27
- Interleukin-17D
- Interleukin 17D
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-27".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-27".
This graph shows the total number of publications written about "Interleukin-27" by people in this website by year, and whether "Interleukin-27" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-27" by people in Profiles.
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TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages. J Innate Immun. 2021; 13(6):345-358.
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IL-17, IL-27, and IL-33: A Novel Axis Linked to Immunological Dysfunction During Sepsis. Front Immunol. 2019; 10:1982.
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Interleukin-27 as a candidate diagnostic biomarker for bacterial infection in immunocompromised pediatric patients. PLoS One. 2018; 13(11):e0207620.
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Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation. PLoS One. 2017; 12(11):e0188387.
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Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells. PLoS Genet. 2017 Mar; 13(3):e1006643.
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Interleukin 27 polymorphisms in HCV RNA positive patients: is there an impact on response to interferon therapy? BMC Infect Dis. 2014; 14 Suppl 5:S5.