Selective Estrogen Receptor Modulators
"Selective Estrogen Receptor Modulators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
| Descriptor ID |
D020845
|
| MeSH Number(s) |
D06.347.360.827 D27.505.696.399.450.360.827
|
| Concept/Terms |
Selective Estrogen Receptor Modulators- Selective Estrogen Receptor Modulators
- SERMs
- Estrogen Receptor Modulators, Selective
- Selective Estrogen Receptor Modulator
- SERM
- Estrogen Receptor Modulator, Selective
|
Below are MeSH descriptors whose meaning is more general than "Selective Estrogen Receptor Modulators".
Below are MeSH descriptors whose meaning is more specific than "Selective Estrogen Receptor Modulators".
This graph shows the total number of publications written about "Selective Estrogen Receptor Modulators" by people in this website by year, and whether "Selective Estrogen Receptor Modulators" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2017 | 3 | 4 | 7 |
| 2018 | 8 | 1 | 9 |
| 2019 | 3 | 1 | 4 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Selective Estrogen Receptor Modulators" by people in Profiles.
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iPSC screening for drug repurposing identifies anti-RNA virus agents modulating host cell susceptibility. FEBS Open Bio. 2021 05; 11(5):1452-1464.
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Raloxifene as a treatment option for viral infections. J Microbiol. 2021 Feb; 59(2):124-131.
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Antiviral drugs targeting endosomal membrane proteins inhibit distant animal and human pathogenic viruses. Antiviral Res. 2021 02; 186:104990.
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Therapeutic potential for clomiphene, a selective estrogen receptor modulator, in the treatment of COVID-19. Med Hypotheses. 2020 12; 145:110354.
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Estradiol, Progesterone, Immunomodulation, and COVID-19 Outcomes. Endocrinology. 2020 09 01; 161(9).
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Raloxifene and Bazedoxifene Could Be Promising Candidates for Preventing the COVID-19 Related Cytokine Storm, ARDS and Mortality. In Vivo. 2020 Sep-Oct; 34(5):3027-3028.
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Ospemifene: A Novel Oral Therapy for Vulvovaginal Atrophy of Menopause. J Obstet Gynaecol Can. 2020 Mar; 42(3):301-303.
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Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 09 03; 322(9):857-867.
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Characterisation of infectious Ebola virus from the ongoing outbreak to guide response activities in the Democratic Republic of the Congo: a phylogenetic and in vitro analysis. Lancet Infect Dis. 2019 09; 19(9):1023-1032.
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Tamoxifen related Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT): A case report and literature review of this possible association. Pathol Res Pract. 2019 May; 215(5):1089-1092.