"beta Karyopherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.
Descriptor ID |
D028961
|
MeSH Number(s) |
D12.776.157.530.750.500.249 D12.776.543.585.750.500.249 D12.776.660.502.500
|
Concept/Terms |
beta Karyopherins- beta Karyopherins
- Karyopherins, beta
- Kap95 protein
- p92 nuclear protein
- nuclear protein, p92
- beta Importins
- Importins, beta
- Karyopherin-beta
- Karyopherin-beta Subunit
- Karyopherin beta Subunit
- Importin-beta
- Importin beta
- Karyopherin beta
|
Below are MeSH descriptors whose meaning is more general than "beta Karyopherins".
Below are MeSH descriptors whose meaning is more specific than "beta Karyopherins".
This graph shows the total number of publications written about "beta Karyopherins" by people in this website by year, and whether "beta Karyopherins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2017 | 3 | 0 | 3 |
2018 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta Karyopherins" by people in Profiles.
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Comparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach. Biophys Chem. 2021 11; 278:106677.
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Repurposing Ivermectin for COVID-19: Molecular Aspects and Therapeutic Possibilities. Front Immunol. 2021; 12:663586.
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Antivirals that target the host IMPa/ß1-virus interface. Biochem Soc Trans. 2021 02 26; 49(1):281-295.
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Importin-ß and exportin-5 are indicators of acute viral infection: Correlation of their detection with commercially available detection kits. Ann Diagn Pathol. 2018 Jun; 34:36-41.
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Importin-ß and exportin-5 are strong biomarkers of productive reoviral infection of cancer cells. Ann Diagn Pathol. 2018 Feb; 32:28-34.
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Increased expression of importin-ß, exportin-5 and nuclear transportable proteins in Alzheimer's disease aids anatomic pathologists in its diagnosis. Ann Diagn Pathol. 2018 Feb; 32:10-16.
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The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol. 2017 03 06; 216(3):641-656.
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Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence. Alcohol Clin Exp Res. 2013 May; 37(5):730-9.
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Severe acute respiratory syndrome coronavirus protein 6 accelerates murine hepatitis virus infections by more than one mechanism. J Virol. 2008 Jul; 82(14):7212-22.
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Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane. J Virol. 2007 Sep; 81(18):9812-24.