"Ion Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.
| Descriptor ID |
D007473
|
| MeSH Number(s) |
D12.776.157.530.400 D12.776.543.550.450 D12.776.543.585.400
|
| Concept/Terms |
Ion Channels- Ion Channels
- Channels, Ion
- Ionic Channels
- Channels, Ionic
- Membrane Channels
- Channels, Membrane
- Ionic Channel
- Channel, Ionic
- Ion Channel
- Channel, Ion
- Membrane Channel
- Channel, Membrane
|
Below are MeSH descriptors whose meaning is more general than "Ion Channels".
Below are MeSH descriptors whose meaning is more specific than "Ion Channels".
This graph shows the total number of publications written about "Ion Channels" by people in this website by year, and whether "Ion Channels" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 7 | 1 | 8 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ion Channels" by people in Profiles.
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Determination of Ligand Binding Modes in Hydrated Viral Ion Channels to Foster Drug Design and Repositioning. J Chem Inf Model. 2021 08 23; 61(8):4011-4022.
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Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity. PLoS Pathog. 2021 05; 17(5):e1009519.
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Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off-label in the first wave of COVID-19. Clin Transl Sci. 2021 05; 14(3):1133-1146.
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COVID-19 Infection and Corrected QT Interval Prolongation-Collateral Damage From Our Newest Enemy. JAMA Netw Open. 2021 04 01; 4(4):e217192.
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Structural biology of coronavirus ion channels. Acta Crystallogr D Struct Biol. 2021 Apr 01; 77(Pt 4):391-402.
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Structural insights into SARS-CoV-2 infection and therapeutics development. Stem Cell Res. 2021 04; 52:102219.
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SARS-CoV-2 3a expression, purification, and reconstitution into lipid nanodiscs. Methods Enzymol. 2021; 653:207-235.
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Lysosomal ion channels involved in cellular entry and uncoating of enveloped viruses: Implications for therapeutic strategies against SARS-CoV-2. Cell Calcium. 2021 03; 94:102360.
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Seven technologies to watch in 2021. Nature. 2021 01; 589(7843):630-632.
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Similarities between the effect of SARS-CoV-2 and HCV on the cellular level, and the possible role of ion channels in COVID19 progression: a review of potential targets for diagnosis and treatment. Channels (Austin). 2020 12; 14(1):403-412.