Pulmonary Surfactant-Associated Protein A
"Pulmonary Surfactant-Associated Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
| Descriptor ID |
D037662
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| MeSH Number(s) |
D12.776.503.280.249.600 D12.776.823.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein A".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein A".
This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein A" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein A" by people in Profiles.
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Immunohistochemical findings in the lungs of COVID-19 subjects: evidence of surfactant dysregulation. Eur Rev Med Pharmacol Sci. 2021 Jul; 25(13):4639-4643.
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Downregulation of type III interferons in patients with severe COVID-19. J Med Virol. 2021 07; 93(7):4559-4563.
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SP-A and SP-D: Dual Functioning Immune Molecules With Antiviral and Immunomodulatory Properties. Front Immunol. 2020; 11:622598.
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Clinical Course of Histologically Proven Multifocal Micronodular Pneumocyte Hyperplasia in Tuberous Sclerosis Complex: A Case Series and Comparison with Lymphangiomyomatosis. Respiration. 2018; 95(5):310-316.
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Lipopolysaccharide Stimulates Surfactant Protein-A in Human Renal Epithelial HK-2 Cells through Upregulating Toll-like Receptor 4 Dependent MEK1/2-ERK1/2-NF-?B Pathway. Chin Med J (Engl). 2017 May 20; 130(10):1236-1243.
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Co-infection of H9N2 subtype avian influenza virus and infectious bronchitis virus decreases SP-A expression level in chickens. Vet Microbiol. 2017 May; 203:110-116.
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Genetic characterization of a Chinese family with familial idiopathic pulmonary fibrosis. Chin Med J (Engl). 2012 Jun; 125(11):1945-51.
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Altered surfactant protein A gene expression and protein homeostasis in rats with emphysematous changes. Chin Med J (Engl). 2008 Jul 05; 121(13):1177-82.