"Receptor, Endothelin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of endothelin receptor found predominantly in the VASCULAR SMOOTH MUSCLE. It has a high affinity for ENDOTHELIN-1 and ENDOTHELIN-2.
| Descriptor ID |
D044022
|
| MeSH Number(s) |
D12.776.543.750.695.220.100 D12.776.543.750.750.320.100
|
| Concept/Terms |
Receptor, Endothelin A- Receptor, Endothelin A
- Endothelin A Receptor
- Endothelin Receptors Type A
- Receptor, Endothelin-1
- Endothelin-1 Receptor
- Receptor, Endothelin 1
- Endothelin A Receptors
- Receptors, Endothelin A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Endothelin A".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Endothelin A".
This graph shows the total number of publications written about "Receptor, Endothelin A" by people in this website by year, and whether "Receptor, Endothelin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 1 | 4 | 5 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Endothelin A" by people in Profiles.
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Why not consider an endothelin receptor antagonist against SARS-CoV-2? Med Hypotheses. 2020 08; 141:109792.
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Downregulation of endothelin A receptor (ETaR) ameliorates renal ischemia reperfusion injury by increasing nitric oxide production. Life Sci. 2019 Jul 01; 228:295-304.
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Is there a role for endothelin-1 receptor antagonists in the treatment of lung fibrosis associated with pulmonary hypertension? Eur Respir J. 2018 08; 52(2).
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Highly Selective Endothelin-1 Receptor A Inhibition Prevents Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice. Respiration. 2018; 95(2):122-136.
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Endothelin-1-induced endothelial mesenchimal transition via endothelin type B receptor stimulation: implication for chronic kidney disease. J Hypertens. 2017 06; 35(6):1329-1330.
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Endothelin-A Receptor Antagonism Retards the Progression of Murine Sickle Cell Nephropathy. J Am Soc Nephrol. 2017 08; 28(8):2253-2255.
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Molecular analysis of vascular smooth muscle cells from patients with giant cell arteritis: Targeting endothelin-1 receptor to control proliferation. Autoimmun Rev. 2017 Apr; 16(4):398-406.
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DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis. Clin Epigenetics. 2017; 9:19.
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Endothelin receptor A antagonism attenuates renal medullary blood flow impairment in endotoxemic pigs. PLoS One. 2011; 6(7):e21534.
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Renal and systemic effects of chronic blockade of ET(A) or ET(B) receptors in normal rats and animals with experimental heart failure. J Cardiovasc Pharmacol. 2004 Nov; 44 Suppl 1:S54-8.