"Podocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly differentiated epithelial cells of the visceral layer of BOWMAN CAPSULE of the KIDNEY. They are composed of a cell body with major CELL SURFACE EXTENSIONS and secondary fingerlike extensions called pedicels. They enwrap the KIDNEY GLOMERULUS capillaries with their cell surface extensions forming a filtration structure. The pedicels of neighboring podocytes interdigitate with each other leaving between them filtration slits that are bridged by an extracellular structure impermeable to large macromolecules called the slit diaphragm, and provide the last barrier to protein loss in the KIDNEY.
| Descriptor ID |
D050199
|
| MeSH Number(s) |
A05.810.453.324.359.372.650 A05.810.453.736.520.720 A11.436.720
|
| Concept/Terms |
Podocytes- Podocytes
- Podocyte
- Glomerular Visceral Epithelial Cells
- Visceral Epithelial Cells, Glomerular
- Epithelial Cells, Glomerular Visceral
|
Below are MeSH descriptors whose meaning is more general than "Podocytes".
Below are MeSH descriptors whose meaning is more specific than "Podocytes".
This graph shows the total number of publications written about "Podocytes" by people in this website by year, and whether "Podocytes" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 17 | 3 | 20 |
| 2018 | 7 | 6 | 13 |
| 2019 | 3 | 3 | 6 |
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Below are the most recent publications written about "Podocytes" by people in Profiles.
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Reinnovating nephrology-a call to action. Kidney Int. 2021 01; 99(1):5-8.
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COVID-19-Associated Glomerular Disease. J Am Soc Nephrol. 2021 01; 32(1):33-40.
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Covid-19 and kidney injury: Pathophysiology and molecular mechanisms. Rev Med Virol. 2021 05; 31(3):e2176.
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Spectrum of podocytopathies in new-onset nephrotic syndrome following COVID-19 disease: a report of 2 cases. BMC Nephrol. 2020 08 04; 21(1):326.
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Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis. Intensive Care Med. 2020 06; 46(6):1114-1116.
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mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans. JCI Insight. 2019 09 19; 4(18).
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Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes. JCI Insight. 2019 09 19; 4(18).
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From podocyte biology to novel cures for glomerular disease. Kidney Int. 2019 10; 96(4):850-861.
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Atypical IgM on T cells predict relapse and steroid dependence in idiopathic nephrotic syndrome. Kidney Int. 2019 10; 96(4):971-982.
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Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis. Kidney Int. 2019 08; 96(2):505-516.