Ataxia Telangiectasia Mutated Proteins
"Ataxia Telangiectasia Mutated Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of PROTEIN-SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.
| Descriptor ID |
D064007
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.097 D12.776.157.687.125 D12.776.660.720.125
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ataxia Telangiectasia Mutated Proteins".
Below are MeSH descriptors whose meaning is more specific than "Ataxia Telangiectasia Mutated Proteins".
This graph shows the total number of publications written about "Ataxia Telangiectasia Mutated Proteins" by people in this website by year, and whether "Ataxia Telangiectasia Mutated Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 8 | 8 | 16 |
| 2018 | 3 | 5 | 8 |
| 2019 | 3 | 2 | 5 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ataxia Telangiectasia Mutated Proteins" by people in Profiles.
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Rapid Classification of COVID-19 Severity by ATR-FTIR Spectroscopy of Plasma Samples. Anal Chem. 2021 08 03; 93(30):10391-10396.
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High Fidelity Deep Sequencing Reveals No Effect of ATM, ATR, and DNA-PK Cellular DNA Damage Response Pathways on Adenovirus Mutation Rate. Viruses. 2019 10 11; 11(10).
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Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells. Cancer Res. 2019 Oct 01; 79(19):4855-4868.
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Alterations in DNA Damage Repair Genes in Primary Liver Cancer. Clin Cancer Res. 2019 08 01; 25(15):4701-4711.
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Individual Radiosensitivity Assessment of the Families of Ataxia-Telangiectasia Patients by G2-Checkpoint Abrogation. Sultan Qaboos Univ Med J. 2018 Nov; 18(4):e440-e446.
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Oxidized ATM-mediated glycolysis enhancement in breast cancer-associated fibroblasts contributes to tumor invasion through lactate as metabolic coupling. EBioMedicine. 2019 Mar; 41:370-383.
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ATM-Mediated Phosphorylation of Cortactin Involved in Actin Polymerization Promotes Breast Cancer Cells Migration and Invasion. Cell Physiol Biochem. 2018; 51(6):2972-2988.
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Coupling between nucleotide excision repair and gene expression. RNA Biol. 2018; 15(7):845-848.
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APE2 promotes DNA damage response pathway from a single-strand break. Nucleic Acids Res. 2018 03 16; 46(5):2479-2494.
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LMTK3 confers chemo-resistance in breast cancer. Oncogene. 2018 06; 37(23):3113-3130.