"Wiskott-Aldrich Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rare, X-linked immunodeficiency syndrome characterized by ECZEMA; LYMPHOPENIA; and, recurrent pyogenic infection. It is seen exclusively in young boys. Typically, IMMUNOGLOBULIN M levels are low and IMMUNOGLOBULIN A and IMMUNOGLOBULIN E levels are elevated. Lymphoreticular malignancies are common.
| Descriptor ID |
D014923
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| MeSH Number(s) |
C15.378.100.100.970 C15.378.463.960 C15.378.553.546.605.900 C16.320.099.970 C16.320.322.937 C20.673.627.900
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| Concept/Terms |
Wiskott-Aldrich Syndrome- Wiskott-Aldrich Syndrome
- Syndrome, Wiskott-Aldrich
- Wiskott Aldrich Syndrome
- Wiskott Syndrome
- Imd2
- Immunodeficiency 2
- Aldrich Syndrome
- Syndrome, Aldrich
- Eczema-Thrombocytopenia-Immunodeficiency Syndrome
- Eczema Thrombocytopenia Immunodeficiency Syndrome
- Eczema-Thrombocytopenia-Immunodeficiency Syndromes
- Syndrome, Eczema-Thrombocytopenia-Immunodeficiency
- Syndromes, Eczema-Thrombocytopenia-Immunodeficiency
|
Below are MeSH descriptors whose meaning is more general than "Wiskott-Aldrich Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Wiskott-Aldrich Syndrome".
This graph shows the total number of publications written about "Wiskott-Aldrich Syndrome" by people in this website by year, and whether "Wiskott-Aldrich Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Wiskott-Aldrich Syndrome" by people in Profiles.
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Mild SARS-CoV-2 Infection After Gene Therapy in a Child With Wiskott-Aldrich Syndrome: A Case Report. Front Immunol. 2020; 11:603428.
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Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study. Lancet Haematol. 2019 May; 6(5):e239-e253.
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Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs. Cell Stem Cell. 2018 Jul 05; 23(1):132-146.e9.
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Screening for Wiskott-Aldrich syndrome by flow cytometry. J Allergy Clin Immunol. 2018 07; 142(1):333-335.e8.
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A risk factor analysis of outcomes after unrelated cord blood transplantation for children with Wiskott-Aldrich syndrome. Haematologica. 2017 06; 102(6):1112-1119.
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[Wiskott-Aldrich syndrome with special phenotypes: report of 3 cases]. Zhongguo Dang Dai Er Ke Za Zhi. 2017 Feb; 19(2):250-253.
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Prevalence of primary immunodeficiency in Korea. J Korean Med Sci. 2012 Jul; 27(7):788-93.
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Macrophages of patients with X-linked thrombocytopenia display an attenuated Wiskott-Aldrich syndrome phenotype. Immunol Cell Biol. 2003 Apr; 81(2):130-6.
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Evidence that defective gamma interferon production in patients with primary immunodeficiencies is due to intrinsic incompetence of lymphocytes. Clin Exp Immunol. 1988 Apr; 72(1):124-9.