"Niclosamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
| Descriptor ID |
D009534
|
| MeSH Number(s) |
D02.065.199.860.470 D02.065.793.650.470 D02.092.146.113.860.470
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Niclosamide".
Below are MeSH descriptors whose meaning is more specific than "Niclosamide".
This graph shows the total number of publications written about "Niclosamide" by people in this website by year, and whether "Niclosamide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2020 | 3 | 0 | 3 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Niclosamide" by people in Profiles.
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Bioanalysis of niclosamide in plasma using liquid chromatography-tandem mass and application to pharmacokinetics in rats and dogs. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 01; 1179:122862.
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Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors. PLoS Pathog. 2021 07; 17(7):e1009706.
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SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals. Nat Commun. 2021 06 21; 12(1):3818.
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Niclosamide inhalation powder made by thin-film freezing: Multi-dose tolerability and exposure in rats and pharmacokinetics in hamsters. Int J Pharm. 2021 Jun 15; 603:120701.
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Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection. Nanoscale. 2021 Apr 07; 13(13):6410-6416.
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Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection. Bioorg Med Chem Lett. 2021 05 15; 40:127906.
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Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae. PLoS One. 2021; 16(2):e0246803.
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Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs. Antimicrob Agents Chemother. 2020 06 23; 64(7).
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Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential. ACS Infect Dis. 2020 05 08; 6(5):909-915.
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Evaluation of the Anti-Tumor Activity of Niclosamide Nanoliposomes Against Colon Carcinoma. Curr Mol Pharmacol. 2020; 13(3):245-250.