"Phenobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
| Descriptor ID |
D010634
|
| MeSH Number(s) |
D03.383.742.698.253.650
|
| Concept/Terms |
Phenobarbital- Phenobarbital
- Phenylbarbital
- Phenylethylbarbituric Acid
- Acid, Phenylethylbarbituric
- Phenemal
- Phenobarbitone
Phenobarbital Sodium- Phenobarbital Sodium
- Sodium, Phenobarbital
- Phenobarbital, Monosodium Salt
- Monosodium Salt Phenobarbital
|
Below are MeSH descriptors whose meaning is more general than "Phenobarbital".
Below are MeSH descriptors whose meaning is more specific than "Phenobarbital".
This graph shows the total number of publications written about "Phenobarbital" by people in this website by year, and whether "Phenobarbital" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 2 | 4 | 6 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Phenobarbital" by people in Profiles.
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Severe cortical damage associated with COVID-19 case report. Seizure. 2021 Jan; 84:66-68.
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Clinical presentation of epilepsy in six villages in an onchocerciasis endemic area in Mahenge, Tanzania. Epileptic Disord. 2019 Oct 01; 21(5):425-435.
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Phenobarbital inhibits osteoclast differentiation and function through NF-?B and MAPKs signaling pathway. Int Immunopharmacol. 2019 Apr; 69:118-125.
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EMPACT Syndrome in a Patient Treated With Phenobarbital. Dermatitis. 2018 Sep/Oct; 29(5):286-288.
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The Safety and Utility of Phenobarbital Use for the Treatment of Severe Alcohol Withdrawal Syndrome in the Medical Intensive Care Unit. J Intensive Care Med. 2020 Sep; 35(9):844-850.
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Renal replacement therapy in severe phenobarbital poisoning: Another brick in the wall. Med Intensiva (Engl Ed). 2019 Oct; 43(7):439-441.
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[New antibiotics - standstill or progress]. Med Klin Intensivmed Notfmed. 2017 Apr; 112(3):206-213.
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MiR-466b-1-3p regulates P-glycoprotein expression in rat cerebral microvascular endothelial cells. Neurosci Lett. 2017 04 03; 645:60-66.
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The emergency medicine management of severe alcohol withdrawal. Am J Emerg Med. 2017 Jul; 35(7):1005-1011.
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Muscone Induces CYP1A2 and CYP3A4 Enzyme Expression in L02 Human Liver Cells and CYP1A2 and CYP3A11 Enzyme Expression in Kunming Mice. Pharmacology. 2017; 99(5-6):205-215.