"Quinacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
| Descriptor ID |
D011796
|
| MeSH Number(s) |
D03.633.300.046.250.760
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Quinacrine".
Below are MeSH descriptors whose meaning is more specific than "Quinacrine".
This graph shows the total number of publications written about "Quinacrine" by people in this website by year, and whether "Quinacrine" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Quinacrine" by people in Profiles.
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Cationic Compounds with SARS-CoV-2 Antiviral Activity and Their Interaction with Organic Cation Transporter/Multidrug and Toxin Extruder Secretory Transporters. J Pharmacol Exp Ther. 2021 10; 379(1):96-107.
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Quinacrine, an Old Drug with Potentially usefull in the Treatment for COVID-19. Arch Med Res. 2021 11; 52(8):858-859.
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The Repurposed Drugs Suramin and Quinacrine Cooperatively Inhibit SARS-CoV-2 3CLpro In Vitro. Viruses. 2021 05 10; 13(5).
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Antimalarial Quinacrine and Chloroquine Lose Their Activity by Decreasing Cationic Amphiphilic Structure with a Slight Decrease in pH. J Med Chem. 2021 04 08; 64(7):3885-3896.
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Quinacrine, an Antimalarial Drug with Strong Activity Inhibiting SARS-CoV-2 Viral Replication In Vitro. Viruses. 2021 Jan 17; 13(1).
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Quinacrine as a potential treatment for COVID-19 virus infection. Eur Rev Med Pharmacol Sci. 2021 01; 25(1):556-566.
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Could the Fight Against Treatment Failures in Giardiasis Lead to a Second Childhood for Quinacrine? J Infect Dis. 2017 11 27; 216(9):1180-1181.
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The Use of Quinacrine in Nitroimidazole-resistant Giardia Duodenalis: An Old Drug for an Emerging Problem. J Infect Dis. 2017 03 15; 215(6):946-953.