Mutagenesis, Site-Directed
"Mutagenesis, Site-Directed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.
| Descriptor ID |
D016297
|
| MeSH Number(s) |
E05.393.420.601.575
|
| Concept/Terms |
Mutagenesis, Site-Directed- Mutagenesis, Site-Directed
- Mutagenesis, Site Directed
- Site-Specific Mutagenesis
- Site Specific Mutagenesis
- Mutagenesis, Site-Specific
- Mutageneses, Site-Specific
- Mutagenesis, Site Specific
- Site-Specific Mutageneses
- Site-Directed Mutagenesis
- Mutageneses, Site-Directed
- Site Directed Mutagenesis
- Site-Directed Mutageneses
Oligonucleotide-Directed Mutagenesis- Oligonucleotide-Directed Mutagenesis
- Oligonucleotide Directed Mutagenesis
- Mutagenesis, Oligonucleotide-Directed
- Mutageneses, Oligonucleotide-Directed
- Mutagenesis, Oligonucleotide Directed
- Oligonucleotide-Directed Mutageneses
|
Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Site-Directed".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Site-Directed".
This graph shows the total number of publications written about "Mutagenesis, Site-Directed" by people in this website by year, and whether "Mutagenesis, Site-Directed" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 5 | 5 |
| 2005 | 1 | 4 | 5 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 4 | 5 |
| 2009 | 0 | 8 | 8 |
| 2010 | 0 | 5 | 5 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 4 | 4 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 17 | 19 |
| 2018 | 1 | 17 | 18 |
| 2019 | 1 | 5 | 6 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 5 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Mutagenesis, Site-Directed" by people in Profiles.
-
A real-time and high-throughput neutralization test based on SARS-CoV-2 pseudovirus containing monomeric infrared fluorescent protein as reporter. Emerg Microbes Infect. 2021 Dec; 10(1):894-904.
-
Structure-based design and characterization of novel fusion-inhibitory lipopeptides against SARS-CoV-2 and emerging variants. Emerg Microbes Infect. 2021 Dec; 10(1):1227-1240.
-
S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity. J Biol Chem. 2021 10; 297(4):101112.
-
1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue. Org Biomol Chem. 2021 08 05; 19(30):6650-6656.
-
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target. Cell Res. 2021 08; 31(8):847-860.
-
Cysteine Modification by Ebselen Reduces the Stability and Cellular Levels of 14-3-3 Proteins. Mol Pharmacol. 2021 08; 100(2):155-169.
-
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell. 2021 11; 12(11):877-888.
-
Molecular dynamics and in silico mutagenesis on the reversible inhibitor-bound SARS-CoV-2 main protease complexes reveal the role of lateral pocket in enhancing the ligand affinity. Sci Rep. 2021 04 01; 11(1):7429.
-
The m6A methylome of SARS-CoV-2 in host cells. Cell Res. 2021 04; 31(4):404-414.
-
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies. MAbs. 2021 Jan-Dec; 13(1):1922134.