"Connexin 43" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.
| Descriptor ID |
D018031
|
| MeSH Number(s) |
D12.776.543.585.250.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Connexin 43".
Below are MeSH descriptors whose meaning is more specific than "Connexin 43".
This graph shows the total number of publications written about "Connexin 43" by people in this website by year, and whether "Connexin 43" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2017 | 8 | 0 | 8 |
| 2018 | 7 | 4 | 11 |
| 2019 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Connexin 43" by people in Profiles.
-
COVID-19 disrupts the blood-testis barrier through the induction of inflammatory cytokines and disruption of junctional proteins. Inflamm Res. 2021 Dec; 70(10-12):1165-1175.
-
TLR2-Dependent Reversible Oxidation of Connexin 43 at Cys260 Modifies Electrical Coupling After Experimental Myocardial Ischemia/Reperfusion. J Cardiovasc Transl Res. 2019 10; 12(5):478-487.
-
Obesity-associated alterations in cardiac connexin-43 and PKC signaling are attenuated by melatonin and omega-3 fatty acids in female rats. Mol Cell Biochem. 2019 Apr; 454(1-2):191-202.
-
mTOR- and SGK-Mediated Connexin 43 Expression Participates in Lipopolysaccharide-Stimulated Macrophage Migration through the iNOS/Src/FAK Axis. J Immunol. 2018 11 15; 201(10):2986-2997.
-
Tumoricidal effect of human olfactory ensheathing cell mediated suicide gene therapy in human glioblastoma cells. Mol Biol Rep. 2018 Dec; 45(6):2263-2273.
-
Syncytial isopotentiality: A system-wide electrical feature of astrocytic networks in the brain. Glia. 2018 12; 66(12):2756-2769.
-
Connexin 43 C-terminus directly inhibits the hyperphosphorylation of Akt/ERK through protein-protein interactions in glioblastoma. Cancer Sci. 2018 Aug; 109(8):2611-2622.
-
ADAMTS13 Deficiency Shortens the Life Span of Mice With Experimental Diabetes. Diabetes. 2018 10; 67(10):2069-2083.
-
Different concentrations of lipopolysaccharide regulate barrier function through the PI3K/Akt signalling pathway in human pulmonary microvascular endothelial cells. Sci Rep. 2018 07 02; 8(1):9963.
-
In vitro formation of the blood-testis barrier during long-term organotypic culture of human prepubertal tissue: comparison with a large cohort of pre/peripubertal boys. Mol Hum Reprod. 2018 05 01; 24(5):271-282.