"Spiro Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic compounds that include two rings which share a single atom (usually a carbon). The simplest example of this type of compound is Spiro[2.2]pentane, which looks like a bow tie.
| Descriptor ID |
D013141
|
| MeSH Number(s) |
D02.455.426.779 D04.711
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Spiro Compounds".
Below are MeSH descriptors whose meaning is more specific than "Spiro Compounds".
This graph shows the total number of publications written about "Spiro Compounds" by people in this website by year, and whether "Spiro Compounds" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2017 | 10 | 0 | 10 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Spiro Compounds" by people in Profiles.
-
Structure-based drug designing and immunoinformatics approach for SARS-CoV-2. Sci Adv. 2020 07; 6(28):eabb8097.
-
Synthesis and anti-coronavirus activity of a series of 1-thia-4-azaspiro[4.5]decan-3-one derivatives. Arch Pharm (Weinheim). 2019 Jun; 352(6):e1800330.
-
Antiviral Meroterpenoid Rhodatin and Sesquiterpenoids Rhodocoranes A-E from the Wrinkled Peach Mushroom, Rhodotus palmatus. Org Lett. 2019 05 03; 21(9):3286-3289.
-
The Utilization of Mu-Opioid Receptor Biased Agonists: Oliceridine, an Opioid Analgesic with Reduced Adverse Effects. Curr Pain Headache Rep. 2019 Mar 18; 23(5):31.
-
DUET: A Phase 2 Study Evaluating the Efficacy and Safety of Sparsentan in Patients with FSGS. J Am Soc Nephrol. 2018 11; 29(11):2745-2754.
-
Meta-analysis of safety and efficacy of rolapitant, NK-1 receptor antagonist for prevention of chemotherapy-induced nausea and vomiting. Curr Probl Cancer. 2018 Mar - Apr; 42(2):241-255.
-
'Biased' opioids could yield safer pain relief. Science. 2017 11 17; 358(6365):847-848.
-
Amorphous solid dispersions of hecogenin acetate using different polymers for enhancement of solubility and improvement of anti-hyperalgesic effect in neuropathic pain model in mice. Biomed Pharmacother. 2018 Jan; 97:870-879.
-
Spirohexene-Tetrazine Ligation Enables Bioorthogonal Labeling of Class B G Protein-Coupled Receptors in Live Cells. J Am Chem Soc. 2017 09 27; 139(38):13376-13386.
-
Inclusion complex between ß-cyclodextrin and hecogenin acetate produces superior analgesic effect in animal models for orofacial pain. Biomed Pharmacother. 2017 Sep; 93:754-762.