"Squalene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A natural 30-carbon triterpene.
| Descriptor ID |
D013185
|
| MeSH Number(s) |
D02.455.326.271.665.806 D02.455.849.919.681
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Squalene".
Below are MeSH descriptors whose meaning is more specific than "Squalene".
This graph shows the total number of publications written about "Squalene" by people in this website by year, and whether "Squalene" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 7 | 8 |
| 2019 | 4 | 2 | 6 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 2 | 3 |
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Below are the most recent publications written about "Squalene" by people in Profiles.
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Evaluating the efficacy of extracted squalene from seed oil in the form of microemulsion for the treatment of COVID-19: A clinical study. J Med Virol. 2022 01; 94(1):119-130.
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Assessment of adjuvantation strategy of lipid squalene nanoparticles for enhancing the immunogenicity of a SARS-CoV-2 spike subunit protein against COVID-19. Int J Pharm. 2021 Sep 25; 607:121024.
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Adjuvanting a subunit COVID-19 vaccine to induce protective immunity. Nature. 2021 06; 594(7862):253-258.
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Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial. Lancet Infect Dis. 2021 10; 21(10):1383-1394.
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Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice. EBioMedicine. 2021 Jan; 63:103197.
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SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation. Immunity. 2020 12 15; 53(6):1281-1295.e5.
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Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents. Sci Adv. 2020 06; 6(23):eaaz5466.
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Recombinant hemagglutinin produced from Chinese Hamster Ovary (CHO) stable cell clones and a PELC/CpG combination adjuvant for H7N9 subunit vaccine development. Vaccine. 2019 11 08; 37(47):6933-6941.
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An indirect comparison meta-analysis of AS03 and MF59 adjuvants in pandemic influenza A(H1N1)pdm09 vaccines. Vaccine. 2019 07 18; 37(31):4246-4255.
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Effectiveness of the trivalent MF59 adjuvated influenza vaccine in preventing hospitalization due to influenza B and A(H1N1)pdm09 viruses in the elderly in Italy, 2017 - 2018 season. Expert Rev Vaccines. 2019 06; 18(6):671-679.