"Neutrophil Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonized particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil.
| Descriptor ID |
D018375
|
| MeSH Number(s) |
G12.604
|
| Concept/Terms |
Neutrophil Activation- Neutrophil Activation
- Activation, Neutrophil
- Activations, Neutrophil
- Neutrophil Activations
|
Below are MeSH descriptors whose meaning is more general than "Neutrophil Activation".
Below are MeSH descriptors whose meaning is more specific than "Neutrophil Activation".
This graph shows the total number of publications written about "Neutrophil Activation" by people in this website by year, and whether "Neutrophil Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2006 | 2 | 1 | 3 |
| 2008 | 1 | 0 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 2 | 3 | 5 |
| 2019 | 1 | 2 | 3 |
| 2020 | 2 | 2 | 4 |
| 2021 | 3 | 7 | 10 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Neutrophil Activation" by people in Profiles.
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Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients: A Case Series and Review of the Literature. Clin Infect Dis. 2022 02 11; 74(3):479-489.
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children. J Clin Invest. 2021 10 15; 131(20).
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Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C. J Clin Invest. 2021 10 15; 131(20).
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Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19. JCI Insight. 2021 09 22; 6(18).
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Neutrophil Extracellular Traps (NETs) in Severe SARS-CoV-2 Lung Disease. Int J Mol Sci. 2021 Aug 17; 22(16).
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Immunoglobulin G Immune Complexes May Contribute to Neutrophil Activation in the Course of Severe Coronavirus Disease 2019. J Infect Dis. 2021 08 16; 224(4):575-585.
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Immunofibrotic drivers of impaired lung function in postacute sequelae of SARS-CoV-2 infection. JCI Insight. 2021 07 22; 6(14).
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Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity. Nat Commun. 2021 07 05; 12(1):4117.
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Enhanced Expression of Autoantigens During SARS-CoV-2 Viral Infection. Front Immunol. 2021; 12:686462.
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Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19. Platelets. 2021 Nov 17; 32(8):1092-1102.