Leukocyte Common Antigens
"Leukocyte Common Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
| Descriptor ID |
D017493
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| MeSH Number(s) |
D08.811.277.352.650.775.400.100.500 D12.644.360.587.100.500 D12.776.476.592.100.500 D12.776.543.733.937.500
|
| Concept/Terms |
Leukocyte Common Antigens- Leukocyte Common Antigens
- Antigens, Leukocyte Common
- CD45 Antigens
- Antigens, CD45
- Protein Tyrosine Phosphatase, Receptor Type, C
- L-CA Antigens
- Antigens, L-CA
- L CA Antigens
- Leukocyte Common Antigen
- Antigen, Leukocyte Common
- CD45 Antigen
- Antigen, CD45
- T200 Antigens
- Antigens, T200
CD45RO Antigens- CD45RO Antigens
- Antigens, CD45RO
- CD45R0 Antigens
- Antigens, CD45R0
B220 Antigens- B220 Antigens
- Antigens, B220
- CD45R Antigens
- Antigens, CD45R
- B220 Antigen
- Antigen, B220
|
Below are MeSH descriptors whose meaning is more general than "Leukocyte Common Antigens".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Common Antigens".
This graph shows the total number of publications written about "Leukocyte Common Antigens" by people in this website by year, and whether "Leukocyte Common Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2017 | 4 | 2 | 6 |
| 2018 | 1 | 5 | 6 |
| 2019 | 0 | 6 | 6 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukocyte Common Antigens" by people in Profiles.
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Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection. Nat Commun. 2021 02 09; 12(1):897.
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SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45- Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein Activates the Nlrp3 Inflammasome. Stem Cell Rev Rep. 2021 02; 17(1):266-277.
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The Systematic Effect of Mesenchymal Stem Cell Therapy in Critical COVID-19 Patients: A Prospective Double Controlled Trial. Cell Transplant. 2021 Jan-Dec; 30:9636897211024942.
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Dynamics of cytokines and lymphocyte subsets associated with the poor prognosis of severe COVID-19. Eur Rev Med Pharmacol Sci. 2020 12; 24(23):12536-12544.
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Evaluating Immune Dysregulation in Patients With COVID-19 Requires a More Accurate Definition of the CD45RA+ T-cell Phenotype. Clin Infect Dis. 2020 11 19; 71(16):2306-2307.
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CD45: a critical regulator in immune cells to predict severe and non-severe COVID-19 patients. Aging (Albany NY). 2020 10 16; 12(20):19867-19879.
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Enumeration of CD34-positive Stem Cells Using the ADAMII Image-based Fluorescence Cell Counter. Ann Lab Med. 2019 Jul; 39(4):388-395.
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Integrated multiomic analysis reveals comprehensive tumour heterogeneity and novel immunophenotypic classification in hepatocellular carcinomas. Gut. 2019 11; 68(11):2019-2031.
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Association of the early absolute CD64-expressing neutrophil count and sepsis outcome. Eur J Clin Microbiol Infect Dis. 2019 Jun; 38(6):1123-1128.
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Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles. J Clin Invest. 2019 03 18; 129(4):1727-1741.