"Centrosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The cell center, consisting of a pair of CENTRIOLES surrounded by a cloud of amorphous material called the pericentriolar region. During interphase, the centrosome nucleates microtubule outgrowth. The centrosome duplicates and, during mitosis, separates to form the two poles of the mitotic spindle (MITOTIC SPINDLE APPARATUS).
| Descriptor ID |
D018385
|
| MeSH Number(s) |
A11.284.430.214.190.750.585.160 A11.284.430.214.190.750.820.500.500
|
| Concept/Terms |
Pericentriolar Region- Pericentriolar Region
- Pericentriolar Regions
- Region, Pericentriolar
- Regions, Pericentriolar
|
Below are MeSH descriptors whose meaning is more general than "Centrosome".
Below are MeSH descriptors whose meaning is more specific than "Centrosome".
This graph shows the total number of publications written about "Centrosome" by people in this website by year, and whether "Centrosome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 2 | 1 | 3 |
| 2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "Centrosome" by people in Profiles.
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Assembly and Cellular Exit of Coronaviruses: Hijacking an Unconventional Secretory Pathway from the Pre-Golgi Intermediate Compartment via the Golgi Ribbon to the Extracellular Space. Cells. 2021 02 26; 10(3).
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COVID-19, cilia, and smell. FEBS J. 2020 09; 287(17):3672-3676.
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Centrosomal protein FOR20 is essential for cilia-dependent development in zebrafish embryos. FASEB J. 2019 03; 33(3):3613-3622.
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Modulation of the Allosteric Communication between the Polo-Box Domain and the Catalytic Domain in Plk1 by Small Compounds. ACS Chem Biol. 2018 08 17; 13(8):1921-1931.
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Centrosome Linker-induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers. Mol Cancer Res. 2018 09; 16(9):1385-1395.
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Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nat Commun. 2017 11 24; 8(1):1773.
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Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1. Nat Commun. 2017 05 05; 8:15289.
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Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids. Cell Stem Cell. 2017 03 02; 20(3):397-406.e5.