Matrix Metalloproteinases
"Matrix Metalloproteinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of zinc-dependent metalloendopeptidases that is involved in the degradation of EXTRACELLULAR MATRIX components.
| Descriptor ID |
D020782
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| MeSH Number(s) |
D08.811.277.656.300.480.525 D08.811.277.656.675.374.525
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinases".
Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinases".
This graph shows the total number of publications written about "Matrix Metalloproteinases" by people in this website by year, and whether "Matrix Metalloproteinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 5 | 6 | 11 |
| 2018 | 3 | 8 | 11 |
| 2019 | 2 | 3 | 5 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Matrix Metalloproteinases" by people in Profiles.
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Matrix metalloproteinases are involved in the development of neurological complications in patients with Coronavirus disease 2019. Int Immunopharmacol. 2021 Nov; 100:108076.
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SARS-CoV-2 and pathological matrix remodeling mediators. Inflamm Res. 2021 Aug; 70(8):847-858.
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Dysregulation of Pulmonary Responses in Severe COVID-19. Viruses. 2021 05 21; 13(6).
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Trace elements and the carotid plaque: the GOOD (Mg, Zn, Se), the UGLY (Fe, Cu), and the BAD (P, Ca)? Eur Rev Med Pharmacol Sci. 2021 05; 25(10):3772-3790.
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The Emerging Role of Epigenetic Mechanisms in the Causation of Aberrant MMP Activity during Human Pathologies and the Use of Medicinal Drugs. Biomolecules. 2021 04 15; 11(4).
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Therapeutic targets in lung tissue remodelling and fibrosis. Pharmacol Ther. 2021 09; 225:107839.
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Targeting MMP-Regulation of Inflammation to Increase Metabolic Tolerance to COVID-19 Pathologies: A Hypothesis. Biomolecules. 2021 03 06; 11(3).
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The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier. Neurobiol Dis. 2020 12; 146:105131.
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Synthesis of N,N'-bis(1,5-dimethyl-2-phenyl-1,2-dihydro-3-oxopyrazol-4-yl) sebacamide that ameliorate osteoarthritis symptoms and improve bone marrow matrix structure and cartilage alterations induced by monoiodoacetate in the rat model: "Suggested potent anti-inflammatory agent against COVID-19". Hum Exp Toxicol. 2021 Feb; 40(2):325-341.
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Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis. ESC Heart Fail. 2020 10; 7(5):2838-2852.