"Chalcones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of CHALCONE that are important intermediates in the formation of FLAVONOIDS with anti-fungal, anti-bacterial, anti-inflammatory, and anti-tumor properties.
| Descriptor ID |
D047188
|
| MeSH Number(s) |
D02.522.818.222 D03.383.663.283.266.450.221 D03.633.100.150.266.450.221
|
| Concept/Terms |
Chalcones- Chalcones
- 1,3-Diphenyl-propenones
- 1,3 Diphenyl propenones
- 1,3-Diphenylpropenones
- 1,3 Diphenylpropenones
- Chalconoids
1,3-Diphenylpropanediones- 1,3-Diphenylpropanediones
- 1,3 Diphenylpropanediones
- 1,3-Diphenyl-propanediones
- 1,3 Diphenyl propanediones
|
Below are MeSH descriptors whose meaning is more general than "Chalcones".
Below are MeSH descriptors whose meaning is more specific than "Chalcones".
This graph shows the total number of publications written about "Chalcones" by people in this website by year, and whether "Chalcones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 4 | 1 | 5 |
| 2018 | 6 | 3 | 9 |
| 2019 | 4 | 0 | 4 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chalcones" by people in Profiles.
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Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry. Pharmacol Res. 2021 10; 172:105820.
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Mechanism deconvolution of Qing Fei Pai Du decoction for treatment of Coronavirus Disease 2019 (COVID-19) by label-free integrative pharmacology assays. J Ethnopharmacol. 2021 Nov 15; 280:114488.
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In vitro inhibition and molecular docking of a new ciprofloxacin-chalcone against SARS-CoV-2 main protease. Fundam Clin Pharmacol. 2022 Feb; 36(1):160-170.
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A comprehensive review on the antiviral activities of chalcones. J Drug Target. 2021 04; 29(4):403-419.
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High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents. Sci Rep. 2020 11 17; 10(1):19963.
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First COVID-19 molecular docking with a chalcone-based compound: synthesis, single-crystal structure and Hirshfeld surface analysis study. Acta Crystallogr C Struct Chem. 2020 12 01; 76(Pt 12):1043-1050.
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Mechanistic insights into dimethyl cardamonin-mediated pharmacological effects: A double control of the AMPK-HMGB1 signaling axis. Life Sci. 2020 Dec 15; 263:118601.
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In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2. Eur J Pharmacol. 2020 Nov 05; 886:173448.
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Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model. Bioorg Med Chem. 2019 10 01; 27(19):115014.
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Licorice isoliquiritigenin-encapsulated mesoporous silica nanoparticles for osteoclast inhibition and bone loss prevention. Theranostics. 2019; 9(18):5183-5199.