"Toll-Like Receptor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
| Descriptor ID |
D051197
|
| MeSH Number(s) |
D12.776.543.750.705.910.500.400
|
| Concept/Terms |
Toll-Like Receptor 4- Toll-Like Receptor 4
- Toll Like Receptor 4
- Toll-4 Receptor
- Toll 4 Receptor
- TLR4 Receptor
- Receptor, TLR4
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 4".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 4".
This graph shows the total number of publications written about "Toll-Like Receptor 4" by people in this website by year, and whether "Toll-Like Receptor 4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 3 | 4 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 2 | 4 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 2 | 4 |
| 2016 | 1 | 3 | 4 |
| 2017 | 24 | 20 | 44 |
| 2018 | 24 | 19 | 43 |
| 2019 | 11 | 7 | 18 |
| 2020 | 2 | 3 | 5 |
| 2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "Toll-Like Receptor 4" by people in Profiles.
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S100A8 may govern hyper-inflammation in severe COVID-19. FASEB J. 2021 09; 35(9):e21798.
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The interplay of DAMPs, TLR4, and proinflammatory cytokines in pulmonary fibrosis. J Mol Med (Berl). 2021 10; 99(10):1373-1384.
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TLR4 involvement in COVID-19 predicts a seasonal risk of Aspergillus superinfection: A call for vigilance. Med Hypotheses. 2021 09; 154:110643.
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Targeting TLR4 Signaling to Blunt Viral-Mediated Acute Lung Injury. Front Immunol. 2021; 12:705080.
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Possible Link between SARS-CoV-2 Infection and Parkinson's Disease: The Role of Toll-Like Receptor 4. Int J Mol Sci. 2021 Jul 01; 22(13).
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Crosstalk of TLR4, vascular NADPH oxidase, and COVID-19 in diabetes: What are the potential implications? Vascul Pharmacol. 2021 08; 139:106879.
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Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4. Immunopharmacol Immunotoxicol. 2021 Jun; 43(3):309-318.
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Toll-like Receptor-4 (TLR4) Agonist-Based Intranasal Nanovaccine Delivery System for Inducing Systemic and Mucosal Immunity. Mol Pharm. 2021 06 07; 18(6):2233-2241.
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The Effects of Insulin-Like Growth Factor I and BTP-2 on Acute Lung Injury. Int J Mol Sci. 2021 May 15; 22(10).
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TLR4 as a therapeutic target for respiratory and neurological complications of SARS-CoV-2. Expert Opin Ther Targets. 2021 Jun; 25(6):491-508.