"Lim Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.
| Descriptor ID |
D054461
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.542 D12.644.360.390 D12.776.476.396 D12.776.512.124
|
| Concept/Terms |
Lim Kinases- Lim Kinases
- Kinases, Lim
- LIM Motif-Containing Protein Kinases
- LIM Motif Containing Protein Kinases
- LIM-Kinase
- LIM Kinase
- Kinase, LIM
|
Below are MeSH descriptors whose meaning is more general than "Lim Kinases".
Below are MeSH descriptors whose meaning is more specific than "Lim Kinases".
This graph shows the total number of publications written about "Lim Kinases" by people in this website by year, and whether "Lim Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Lim Kinases" by people in Profiles.
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LIMK2 acts as an oncogene in bladder cancer and its functional SNP in the microRNA-135a binding site affects bladder cancer risk. Int J Cancer. 2019 03 15; 144(6):1345-1355.
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Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells. Food Chem Toxicol. 2018 Mar; 113:328-336.
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Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2. Circulation. 2017 Dec 19; 136(25):2451-2467.
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miR-29a/b/c function as invasion suppressors for gliomas by targeting CDC42 and predict the prognosis of patients. Br J Cancer. 2017 Sep 26; 117(7):1036-1047.
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Whole Exome Sequencing Identifies Rare Protein-Coding Variants in Behçet's Disease. Arthritis Rheumatol. 2016 05; 68(5):1272-80.