"Isoindoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Benzopyrroles with the nitrogen at the number two carbon, in contrast to INDOLES which have the nitrogen adjacent to the six-membered ring.
| Descriptor ID |
D054833
|
| MeSH Number(s) |
D03.633.100.513
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Isoindoles".
Below are MeSH descriptors whose meaning is more specific than "Isoindoles".
This graph shows the total number of publications written about "Isoindoles" by people in this website by year, and whether "Isoindoles" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 3 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Isoindoles" by people in Profiles.
-
What Binds Cationic Photosensitizers Better: Brownian Dynamics Reveals Key Interaction Sites on Spike Proteins of SARS-CoV, MERS-CoV, and SARS-CoV-2. Viruses. 2021 08 15; 13(8).
-
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease. Biochem J. 2021 07 16; 478(13):2499-2515.
-
Ebselen and Analogues: Pharmacological Properties and Synthetic Strategies for Their Preparation. Molecules. 2021 Jul 12; 26(14).
-
Cysteine Modification by Ebselen Reduces the Stability and Cellular Levels of 14-3-3 Proteins. Mol Pharmacol. 2021 08; 100(2):155-169.
-
Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives. Nat Commun. 2021 05 24; 12(1):3061.
-
In silico Studies on the Interaction between Mpro and PLpro From SARS-CoV-2 and Ebselen, its Metabolites and Derivatives. Mol Inform. 2021 08; 40(8):e2100028.
-
The Photosensitizer Octakis(cholinyl)zinc Phthalocyanine with Ability to Bind to a Model Spike Protein Leads to a Loss of SARS-CoV-2 Infectivity In Vitro When Exposed to Far-Red LED. Viruses. 2021 04 09; 13(4).
-
Ebsulfur and Ebselen as highly potent scaffolds for the development of potential SARS-CoV-2 antivirals. Bioorg Chem. 2021 07; 112:104889.
-
Toxicology and pharmacology of synthetic organoselenium compounds: an update. Arch Toxicol. 2021 04; 95(4):1179-1226.
-
Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2. Sci Rep. 2021 02 11; 11(1):3640.