"Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
    
    
        
            
            
                A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
    
            
            
                
                    
                        
                            | Descriptor ID | 
                            
                                D015847
                             | 
                        
                        
                            | MeSH Number(s) | 
                            
                                 D12.644.276.374.465.186 D12.776.467.374.465.178 D23.529.374.465.186 
                             | 
                        
                        
                            | Concept/Terms | 
                            
                                Interleukin-4- Interleukin-4
 - Interleukin 4
 - B-Cell Growth Factor-1
 - B Cell Growth Factor 1
 - B-Cell Growth Factor-I
 - B Cell Growth Factor I
 - B-Cell Proliferating Factor
 - B Cell Proliferating Factor
 - B-Cell Stimulating Factor-1
 - B Cell Stimulating Factor 1
 - B-Cell Stimulatory Factor 1
 - B-Cell Stimulatory Factor-1
 - BCGF-1
 - Binetrakin
 - BSF-1
 - IL-4
 - IL4
 - Mast Cell Growth Factor-2
 - Mast Cell Growth Factor 2
 - MCGF-2
 - B Cell Stimulatory Factor-1
 - B Cell Stimulatory Factor 1
 
  
                             | 
                        
                    
                
             
            
                Below are MeSH descriptors whose meaning is more general than "Interleukin-4".
                
             
            
            
                Below are MeSH descriptors whose meaning is more specific than "Interleukin-4".
                
             
         
     
 
                                            
                                                
	
	
		
			
			
					
				This graph shows the total number of publications written about "Interleukin-4" by people in this website by year, and whether "Interleukin-4" was a major or minor topic of these publications. 
				
					
                    To see the data from this visualization as text, 
click here. 
				 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1997 | 1 | 1 | 2 | 
| 1998 | 1 | 1 | 2 | 
| 1999 | 0 | 2 | 2 | 
| 2000 | 0 | 1 | 1 | 
| 2002 | 0 | 1 | 1 | 
| 2003 | 0 | 2 | 2 | 
| 2004 | 0 | 1 | 1 | 
| 2005 | 0 | 1 | 1 | 
| 2006 | 1 | 0 | 1 | 
| 2007 | 0 | 1 | 1 | 
| 2008 | 1 | 2 | 3 | 
| 2009 | 0 | 1 | 1 | 
| 2010 | 1 | 1 | 2 | 
| 2011 | 0 | 1 | 1 | 
| 2014 | 1 | 4 | 5 | 
| 2016 | 1 | 1 | 2 | 
| 2017 | 12 | 27 | 39 | 
| 2018 | 6 | 20 | 26 | 
| 2019 | 2 | 1 | 3 | 
| 2020 | 2 | 1 | 3 | 
| 2021 | 0 | 5 | 5 | 
                   To return to the timeline, click here.
                 
			 	
			
			
			
			
				Below are the most recent publications written about "Interleukin-4" by people in Profiles.
						
					
								- 
								
Changes of serum IL-10, IL-1ß, IL-6, MCP-1, TNF-a, IP-10 and IL-4 in COVID-19 patients. Int J Clin Pract. 2021 Sep; 75(9):e14462.
															
								 
							
								- 
								
Chronic Immune Activation and CD4+ T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy. Front Immunol. 2021; 12:693269.
															
								 
							
								- 
								
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways. PLoS Pathog. 2021 06; 17(6):e1009662.
															
								 
							
								- 
								
Different T cell related immunological profiles in COVID-19 patients compared to healthy controls. Int Immunopharmacol. 2021 Aug; 97:107828.
															
								 
							
								- 
								
Peripheral and lung resident memory T cell responses against SARS-CoV-2. Nat Commun. 2021 05 21; 12(1):3010.
															
								 
							
								- 
								
Analysis of cytokines in SARS-CoV-2 or COVID-19 patients in Erbil city, Kurdistan Region of Iraq. PLoS One. 2021; 16(4):e0250330.
															
								 
							
								- 
								
A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice. Mol Ther. 2021 06 02; 29(6):1970-1983.
															
								 
							
								- 
								
SARS-CoV-2 infection and COVID-19 in asthmatics: a complex relationship. Nat Rev Immunol. 2021 04; 21(4):202-203.
															
								 
							
								- 
								
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations. Cells. 2021 02 13; 10(2).
															
								 
							
								- 
								
Differences in Immune Responses between Children and Adults with COVID-19. Curr Med Sci. 2021 Feb; 41(1):58-61.