"CpG Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.
| Descriptor ID |
D018899
|
| MeSH Number(s) |
G02.111.570.080.380.160 G05.360.080.380.160 G05.360.340.024.159
|
| Concept/Terms |
CpG Islands- CpG Islands
- CpG Island
- Island, CpG
- Islands, CpG
- CpG-Rich Islands
- CpG Rich Islands
- CpG-Rich Island
- Island, CpG-Rich
- Islands, CpG-Rich
CpG Clusters- CpG Clusters
- Cluster, CpG
- Clusters, CpG
- CpG Cluster
|
Below are MeSH descriptors whose meaning is more general than "CpG Islands".
Below are MeSH descriptors whose meaning is more specific than "CpG Islands".
This graph shows the total number of publications written about "CpG Islands" by people in this website by year, and whether "CpG Islands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 26 | 28 |
| 2018 | 6 | 15 | 21 |
| 2019 | 1 | 6 | 7 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 2 | 3 |
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Below are the most recent publications written about "CpG Islands" by people in Profiles.
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Methylation of Host Genes Associated with Coronavirus Infection from Birth to 26 Years. Genes (Basel). 2021 07 31; 12(8).
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Short sequence motif dynamics in the SARS-CoV-2 genome suggest a role for cytosine deamination in CpG reduction. J Mol Cell Biol. 2021 07 06; 13(3):225-227.
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An epigenome-wide DNA methylation study of patients with COVID-19. Ann Hum Genet. 2021 11; 85(6):221-234.
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Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 Survivors. Int J Mol Sci. 2021 Jun 07; 22(11).
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SARS-CoV-2 and other human coronavirus show genome patterns previously associated to reduced viral recognition and altered immune response. Sci Rep. 2021 05 21; 11(1):10696.
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The Heterogeneous Landscape and Early Evolution of Pathogen-Associated CpG Dinucleotides in SARS-CoV-2. Mol Biol Evol. 2021 05 19; 38(6):2428-2445.
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Epigenome-wide association study of COVID-19 severity with respiratory failure. EBioMedicine. 2021 Apr; 66:103339.
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SARS-CoV-2 hot-spot mutations are significantly enriched within inverted repeats and CpG island loci. Brief Bioinform. 2021 03 22; 22(2):1338-1345.
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Evolution of Transmissible Gastroenteritis Virus (TGEV): A Codon Usage Perspective. Int J Mol Sci. 2020 Oct 24; 21(21).
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SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans. mBio. 2020 10 16; 11(5).