"Glycocalyx" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The carbohydrate-rich zone on the cell surface. This zone can be visualized by a variety of stains as well as by its affinity for lectins. Although most of the carbohydrate is attached to intrinsic plasma membrane molecules, the glycocalyx usually also contains both glycoproteins and proteoglycans that have been secreted into the extracellular space and then adsorbed onto the cell surface. (Alberts et al., Molecular Biology of the Cell, 3d ed, p502)
| Descriptor ID |
D019276
|
| MeSH Number(s) |
A11.284.149.165.355
|
| Concept/Terms |
Glycocalyx- Glycocalyx
- Glycocalix
- Cell Coat
- Cell Coats
- Coat, Cell
- Coats, Cell
|
Below are MeSH descriptors whose meaning is more general than "Glycocalyx".
Below are MeSH descriptors whose meaning is more specific than "Glycocalyx".
This graph shows the total number of publications written about "Glycocalyx" by people in this website by year, and whether "Glycocalyx" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 5 | 1 | 6 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycocalyx" by people in Profiles.
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Association of COVID-19 with impaired endothelial glycocalyx, vascular function and myocardial deformation 4 months after infection. Eur J Heart Fail. 2021 11; 23(11):1916-1926.
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COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction. JCI Insight. 2021 09 08; 6(17).
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[Impairment of the microculation in COVID-19]. Med Klin Intensivmed Notfmed. 2021 Sep; 116(6):530-534.
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Endothelial glycocalyx shields the interaction of SARS-CoV-2 spike protein with ACE2 receptors. Sci Rep. 2021 06 09; 11(1):12157.
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Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients. Life Sci. 2021 Jul 01; 276:119376.
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Glycocalyx as Possible Limiting Factor in COVID-19. Front Immunol. 2021; 12:607306.
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Vascular Endothelial Glycocalyx Damage in COVID-19. Int J Mol Sci. 2020 Dec 19; 21(24).
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Injury to the Endothelial Glycocalyx in Critically Ill Patients with COVID-19. Am J Respir Crit Care Med. 2020 10 15; 202(8):1178-1181.
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Microvascular dysfunction in COVID-19: the MYSTIC study. Angiogenesis. 2021 02; 24(1):145-157.
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Vascular endothelial injury exacerbates coronavirus disease 2019: The role of endothelial glycocalyx protection. Microcirculation. 2021 04; 28(3):e12654.