"Endothelin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
| Descriptor ID |
D019332
|
| MeSH Number(s) |
D12.644.276.400.225 D12.776.467.400.225 D23.529.400.225
|
| Concept/Terms |
Proendothelin (1-38)- Proendothelin (1-38)
- Big Endothelin
- Big Endothelin-1
- Big Endothelin 1
- Endothelin-1, Big
- Endothelin, Big
Preproendothelin-1- Preproendothelin-1
- Preproendothelin 1
- Preproendothelin
- Proendothelin-1 Precursor
- Precursor, Proendothelin-1
- Proendothelin 1 Precursor
|
Below are MeSH descriptors whose meaning is more general than "Endothelin-1".
Below are MeSH descriptors whose meaning is more specific than "Endothelin-1".
This graph shows the total number of publications written about "Endothelin-1" by people in this website by year, and whether "Endothelin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 6 | 3 | 9 |
| 2018 | 2 | 4 | 6 |
| 2019 | 1 | 4 | 5 |
| 2021 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Endothelin-1" by people in Profiles.
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Endothelium-associated biomarkers mid-regional proadrenomedullin and C-terminal proendothelin-1 have good ability to predict 28-day mortality in critically ill patients with SARS-CoV-2 pneumonia: A prospective cohort study. J Crit Care. 2021 12; 66:173-180.
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Association of endothelial activation assessed through endothelin-I precursor peptide measurement with mortality in COVID-19 patients: an observational analysis. Respir Res. 2021 May 13; 22(1):148.
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Endothelin antagonism and sodium glucose Co-transporter 2 inhibition. A potential combination therapeutic strategy for COVID-19. Pulm Pharmacol Ther. 2021 08; 69:102035.
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Design of a study to investigate the mechanisms of obstructive sleep apnoea by means of drug-induced sleep endoscopy. Clin Chem Lab Med. 2019 08 27; 57(9):1406-1413.
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Effect of Acute Altitude Exposure on Serum Markers of Platelet Activation. High Alt Med Biol. 2019 09; 20(3):318-321.
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Is circulating endothelin evaluation useful for clinicians? Intern Emerg Med. 2019 10; 14(7):1029-1031.
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Effects of granulocyte colony-stimulating factor on rabbit carotid and porcine heart models of chronic obliterative arterial disease. Mol Med Rep. 2019 Jun; 19(6):4569-4578.
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Endothelin-1/nitric oxide balance and HOMA index in children with excess weight and hypertension: a pathophysiological model of hypertension. Hypertens Res. 2019 08; 42(8):1192-1199.
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High preoperative plasma endothelin-1 levels are associated with increased acute kidney injury risk after pulmonary endarterectomy. J Nephrol. 2018 Dec; 31(6):881-888.
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Novel biochemical predictors of unfavorable prognosis for stable coronary disease. Medicine (Baltimore). 2018 Sep; 97(37):e12372.